Association of spinal muscle composition and prevalence of hyperkyphosis in healthy community-dwelling older men and women

Wendy Katzman, Peggy Cawthon, Gregory E. Hicks, Eric Vittinghoff, John Shepherd, Jane A. Cauley, Tamara Harris, Eleanor M. Simonsick, Elsa Strotmeyer, Catherine Womack, Deborah M. Kado

Research output: Contribution to journalArticle

Abstract

Background. Older adults with hyperkyphosis are at increased risk of falls, fractures, and functional decline. Modifiable risk factors for hyperkyphosis have not been well studied. Our objective was to determine whether spinal muscle area and density are associated with hyperkyphosis, independent of age, race, sex, bone mineral density, and trunk fat. Methods. Using data from the Pittsburgh site of the Health, Aging, and Body Composition study, we performed a baseline cross-sectional analysis. Participants were black and white men and women 70-79 years old (N = 1172), independent in activities of daily living and able to walk mile and up 10 steps without resting. We measured Cobb's angle of kyphosis from supine lateral scout computed tomography scans, and categorized hyperkyphosis as Cobb's angle >40. Axial images from lateral scout computed tomography scans assessed spinal extensor muscle cross-sectional area and density (proxy for fat infiltration). Results. In our sample, 21% had hyperkyphosis. Prevalence in black men was 11%; in white men, 17%; in black women, 26%; and in white women, 30%. In multivariate analysis, each standard deviation increase in muscle density was associated with a 29% reduction in the odds of hyperkyphosis, independent of covariates. Muscle area was not significantly associated with hyperkyphosis. Conclusions. Lower spinal muscle density is associated with hyperkyphosis in healthy community-dwelling older adults. This potentially modifiable risk factor could be targeted in exercise interventions. Randomized trials are needed to determine whether an exercise program targeting spinal muscle density reduces hyperkyphosis and in turn improves health outcomes.

Original languageEnglish (US)
Pages (from-to)191-195
Number of pages5
JournalJournals of Gerontology - Series A Biological Sciences and Medical Sciences
Volume67 A
Issue number2
DOIs
StatePublished - Feb 1 2012

Keywords

  • Fat infiltration
  • Hyperkyphosis
  • Kyphosis
  • Prevalence
  • Spinal muscle

ASJC Scopus subject areas

  • Aging
  • Geriatrics and Gerontology

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    Katzman, W., Cawthon, P., Hicks, G. E., Vittinghoff, E., Shepherd, J., Cauley, J. A., Harris, T., Simonsick, E. M., Strotmeyer, E., Womack, C., & Kado, D. M. (2012). Association of spinal muscle composition and prevalence of hyperkyphosis in healthy community-dwelling older men and women. Journals of Gerontology - Series A Biological Sciences and Medical Sciences, 67 A(2), 191-195. https://doi.org/10.1093/gerona/glr160