TY - JOUR
T1 - Association of physical activity and vascular stiffness in 70- to 79-year-olds
T2 - The Health ABC study
AU - Havlik, Richard J.
AU - Simonsick, Eleanor M.
AU - Sutton-Tyrrell, Kim
AU - Newman, Anne
AU - Danielson, Michelle E.
AU - Brock, Dwight B.
AU - Pahor, Marco
AU - Lakatta, Edward
AU - Spurgeon, Harold
AU - Vaitkevicius, Peter
PY - 2003/4
Y1 - 2003/4
N2 - Although it is well established that stiff blood vessels contribute to systolic hypertension and increased cardiovascular disease with aging, risk factors for vascular stiffness are still being defined. The Health, Aging, and Body Composition study is a longitudinal investigation of the determinants of physical-functional decline in a well-functioning biracial cohort of 3,075 men and women, age 70-79, in Pittsburgh, PA, and Memphis, TN. Aortic pulse-wave velocity (APWV), an index of vascular stiffness, was measured in 2,488 participants. Self-reported physical activity and exercise habits and fitness/walking endurance were also assessed. Moderate or greater physical activity, exercise, and fitness variables were independently associated with less vascular stiffness, even after inclusion of heart rate, visceral fat, and other correlates of APWV. Physical activity's association with APWV was particularly strong when levels of physical activity were quite low, suggesting that a minimal amount of physical activity might be sufficient to reduce arterial stiffness in older adults.
AB - Although it is well established that stiff blood vessels contribute to systolic hypertension and increased cardiovascular disease with aging, risk factors for vascular stiffness are still being defined. The Health, Aging, and Body Composition study is a longitudinal investigation of the determinants of physical-functional decline in a well-functioning biracial cohort of 3,075 men and women, age 70-79, in Pittsburgh, PA, and Memphis, TN. Aortic pulse-wave velocity (APWV), an index of vascular stiffness, was measured in 2,488 participants. Self-reported physical activity and exercise habits and fitness/walking endurance were also assessed. Moderate or greater physical activity, exercise, and fitness variables were independently associated with less vascular stiffness, even after inclusion of heart rate, visceral fat, and other correlates of APWV. Physical activity's association with APWV was particularly strong when levels of physical activity were quite low, suggesting that a minimal amount of physical activity might be sufficient to reduce arterial stiffness in older adults.
KW - Aging
KW - Exercise
KW - Pulse-wave velocity
UR - http://www.scopus.com/inward/record.url?scp=0037386950&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0037386950&partnerID=8YFLogxK
U2 - 10.1123/japa.11.2.156
DO - 10.1123/japa.11.2.156
M3 - Article
AN - SCOPUS:0037386950
SN - 1063-8652
VL - 11
SP - 156
EP - 166
JO - Journal of Aging and Physical Activity
JF - Journal of Aging and Physical Activity
IS - 2
ER -