Association of parvovirus B19 with plasma cell-rich myocardial infiltrates after heart transplantation

Fritz E. Lower, Santosh Menon, Juan A. Sanchez

Research output: Contribution to journalArticlepeer-review

Abstract

In this report we describe the development of plasma cell-rich myocardial infiltrates in association with a parvovirus B19 infection in a heart transplant patient. We hypothesize that the virus, either alone or in association with the cardiac allograft, may polarize the immune response in the direction of T helper 2 (Th2) cells rather than the expected Th1 cells. This favors the development of a humoral immune response and infiltration of the graft with plasma cells.

Original languageEnglish (US)
Pages (from-to)755-758
Number of pages4
JournalJournal of Heart and Lung Transplantation
Volume20
Issue number7
DOIs
StatePublished - Jul 24 2001
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine
  • Transplantation

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