Association of injection practices and overdose with drug use typologies: A latent class analysis among people who inject drugs in baltimore, 2017

Rachel E. Gicquelais, Becky Genberg, Jacquie Astemborski, David D Celentano, Gregory D Kirk, Shruti Hemendra Mehta

Research output: Contribution to journalArticle

Abstract

Increasing overdose mortality and new HIV outbreaks in the U.S. highlight the need to identify risk behavior profiles among people who inject drugs (PWID). We characterized latent classes of drug use among a communitybased sample of 671 PWID in Baltimore during 2017 and evaluated associations of these classes with sharing syringes, obtaining syringes from pharmacies or syringe services programs (SSPs), and nonfatal overdose in the past 6 months. We identified three classes of current drug use: infrequent use (76% of participants), prescription drug use (12%), and heroin and/or cocaine injection (12%). PWID in the heroin and/or cocaine injection and prescription drug use classes had higher odds of both overdose and sharing syringes (relative to infrequent use). PWID in the prescription drug use class were 64% less likely to obtain syringes through SSPs/pharmacies relative to heroin and/or cocaine injection. Harm reduction programs need to engage people who obtain prescription drugs illicitly.

Original languageEnglish (US)
Pages (from-to)344-362
Number of pages19
JournalAIDS Education and Prevention
Volume31
Issue number4
DOIs
StatePublished - Jan 1 2019

Fingerprint

Drug Overdose
Baltimore
Prescription Drugs
drug use
Syringes
typology
drug
Heroin
medication
Injections
Cocaine
Needle Sharing
Pharmaceutical Preparations
Harm Reduction
Drug Prescriptions
Pharmaceutical Services
Pharmacies
Risk-Taking
risk behavior
Disease Outbreaks

Keywords

  • Harm reduction
  • Latent class analysis
  • Overdose
  • People who inject drugs
  • Syringe sharing

ASJC Scopus subject areas

  • Health(social science)
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

Cite this

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abstract = "Increasing overdose mortality and new HIV outbreaks in the U.S. highlight the need to identify risk behavior profiles among people who inject drugs (PWID). We characterized latent classes of drug use among a communitybased sample of 671 PWID in Baltimore during 2017 and evaluated associations of these classes with sharing syringes, obtaining syringes from pharmacies or syringe services programs (SSPs), and nonfatal overdose in the past 6 months. We identified three classes of current drug use: infrequent use (76{\%} of participants), prescription drug use (12{\%}), and heroin and/or cocaine injection (12{\%}). PWID in the heroin and/or cocaine injection and prescription drug use classes had higher odds of both overdose and sharing syringes (relative to infrequent use). PWID in the prescription drug use class were 64{\%} less likely to obtain syringes through SSPs/pharmacies relative to heroin and/or cocaine injection. Harm reduction programs need to engage people who obtain prescription drugs illicitly.",
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