Association of Helicobacter pylori infection with dyspeptic symptoms in patients undergoing gastroduodenoscopy

Robert M. Strauss; Timothy C. Wang; Peter B. Kelsey; Carolyn C. Compton; Mary Jane Ferraro; Guillermo Perez-Perez; Julie Parsonnet; Martin J. Blaser

doi:10.1016/0002-9343(90)90377-P

Association of Helicobacter pylori infection with dyspeptic symptoms in patients undergoing gastroduodenoscopy

Robert M. Strauss, Timothy C. Wang, Peter B. Kelsey, Carolyn C. Compton, Mary Jane Ferraro, Guillermo Perez-Perez, Julie Parsonnet, Martin J. Blaser

Research output: Contribution to journal › Article › peer-review

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Abstract

purpose: To determine the prevalence of Helicobacter pylori in patients with non-ulcer dyspepsia and ulcer disease as well as in a control population undergoing endoscopic retrograde cholangiopancreatography (ERCP) for suspected pancreatic or biliary disease. patients and methods: Forty-six eligible patients undergoing upper endoscopy at Massachusetts General Hospital were studied over a period of 18 months, as well as 24 patients undergoing ERCP for presumed pancreatic or biliary disease. Two biopsy specimens from the fundus and two from the antrum were taken for microbiologic and histopathologic analysis. Sera were examined by enzyme-linked immunoabsorbent assay. All specimens were processed in a blind fashion. Chi-square test with Yates' correction was used for statistical analysis. results: H. pylori was found in 31 of 46 (67%) study patients and in six of 24 (25%) control patients (by microbiologic or histologic techniques) (p

Original language	English (US)
Pages (from-to)	464-469
Number of pages	6
Journal	American Journal of Medicine
Volume	89
Issue number	4
DOIs	https://doi.org/10.1016/0002-9343(90)90377-P
State	Published - 1990
Externally published	Yes

ASJC Scopus subject areas

General Nursing

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title = "Association of Helicobacter pylori infection with dyspeptic symptoms in patients undergoing gastroduodenoscopy",

abstract = "purpose: To determine the prevalence of Helicobacter pylori in patients with non-ulcer dyspepsia and ulcer disease as well as in a control population undergoing endoscopic retrograde cholangiopancreatography (ERCP) for suspected pancreatic or biliary disease. patients and methods: Forty-six eligible patients undergoing upper endoscopy at Massachusetts General Hospital were studied over a period of 18 months, as well as 24 patients undergoing ERCP for presumed pancreatic or biliary disease. Two biopsy specimens from the fundus and two from the antrum were taken for microbiologic and histopathologic analysis. Sera were examined by enzyme-linked immunoabsorbent assay. All specimens were processed in a blind fashion. Chi-square test with Yates' correction was used for statistical analysis. results: H. pylori was found in 31 of 46 (67%) study patients and in six of 24 (25%) control patients (by microbiologic or histologic techniques) (p ",

author = "Strauss, {Robert M.} and Wang, {Timothy C.} and Kelsey, {Peter B.} and Compton, {Carolyn C.} and Ferraro, {Mary Jane} and Guillermo Perez-Perez and Julie Parsonnet and Blaser, {Martin J.}",

year = "1990",

doi = "10.1016/0002-9343(90)90377-P",

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T1 - Association of Helicobacter pylori infection with dyspeptic symptoms in patients undergoing gastroduodenoscopy

AU - Strauss, Robert M.

AU - Wang, Timothy C.

AU - Kelsey, Peter B.

AU - Compton, Carolyn C.

AU - Ferraro, Mary Jane

AU - Perez-Perez, Guillermo

AU - Parsonnet, Julie

AU - Blaser, Martin J.

PY - 1990

Y1 - 1990

N2 - purpose: To determine the prevalence of Helicobacter pylori in patients with non-ulcer dyspepsia and ulcer disease as well as in a control population undergoing endoscopic retrograde cholangiopancreatography (ERCP) for suspected pancreatic or biliary disease. patients and methods: Forty-six eligible patients undergoing upper endoscopy at Massachusetts General Hospital were studied over a period of 18 months, as well as 24 patients undergoing ERCP for presumed pancreatic or biliary disease. Two biopsy specimens from the fundus and two from the antrum were taken for microbiologic and histopathologic analysis. Sera were examined by enzyme-linked immunoabsorbent assay. All specimens were processed in a blind fashion. Chi-square test with Yates' correction was used for statistical analysis. results: H. pylori was found in 31 of 46 (67%) study patients and in six of 24 (25%) control patients (by microbiologic or histologic techniques) (p

AB - purpose: To determine the prevalence of Helicobacter pylori in patients with non-ulcer dyspepsia and ulcer disease as well as in a control population undergoing endoscopic retrograde cholangiopancreatography (ERCP) for suspected pancreatic or biliary disease. patients and methods: Forty-six eligible patients undergoing upper endoscopy at Massachusetts General Hospital were studied over a period of 18 months, as well as 24 patients undergoing ERCP for presumed pancreatic or biliary disease. Two biopsy specimens from the fundus and two from the antrum were taken for microbiologic and histopathologic analysis. Sera were examined by enzyme-linked immunoabsorbent assay. All specimens were processed in a blind fashion. Chi-square test with Yates' correction was used for statistical analysis. results: H. pylori was found in 31 of 46 (67%) study patients and in six of 24 (25%) control patients (by microbiologic or histologic techniques) (p

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Association of Helicobacter pylori infection with dyspeptic symptoms in patients undergoing gastroduodenoscopy

Abstract

ASJC Scopus subject areas

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