Association of Epstein-Barr virus with acute exudative tonsillitis

D. Grady, J. E. McClung, R. W. Veltri, P. M. Sprinkle, J. S. Veach

Research output: Contribution to journalArticlepeer-review


This report is concerned with acute exudative tonsillitis as a pathologic response to the Epstein-Barr virus (EPV). The concept of a bacterial-viral etiology for tonsillitis has been suggested, and previous studies implicate EBV as a major pathogen in exudative tonsillitis. A prospective study of 16 patients with this diagnosis was conducted. EBV serologic data plus viral and bacterial throat cultures were compiled and evaluated. EBV as a causal agent alone or concurrent with other organisms was seen in 56% (9) of the patients under study. EBV activation was associated with infection by other organisms in 19% (3) of the cases. The overall total incidence of EBV in association with severe acute exudative tonsillitis was 75% (12). The data further documents EBV as a significant causal or associative agent in acute exudative tonsillitis.

Original languageEnglish (US)
Pages (from-to)11-15
Number of pages5
JournalUnknown Journal
Issue number1
StatePublished - Jan 1 1982

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology

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