TY - JOUR
T1 - Association of dietary total antioxidant capacity to anthropometry in healthy women
T2 - A cross-sectional study
AU - Mozaffari, Hadis
AU - Daneshzad, Elnaz
AU - Larijani, Bagher
AU - Surkan, Pamela J.
AU - Azadbakht, Leila
N1 - Funding Information:
This study was supported by the Endocrinology and Metabolism Research Institute, Tehran University of Medical Sciences (grant no. 1397-01-105-2263). The Endocrinology and Metabolism Research Institute had no role in the design, analysis, or writing of this article. HM and LA designed the study. HM, ED, BL, PJS, and LA contributed to the statistical analysis, interpretation of the data and drafting of the manuscript. The final version of manuscript for submission was approved by all authors. The authors have no conflicts of interest to declare.
Publisher Copyright:
© 2019
PY - 2020/1
Y1 - 2020/1
N2 - Objectives: Reactive oxygen species level is a fundamental component in the pathogenesis of obesity that might be reduced by dietary antioxidants. Measurement of dietary total antioxidant capacity (DTAC) is regarded as a new holistic dietary index. Given the limited research on DTAC, the aim of this study was to examine the association of DTAC with obesity-related features in women. Methods: The present cross-sectional study included 627 female participants. Data on dietary intake were assessed using a validated food frequency questionnaire. DTAC was estimated through total reactive antioxidant potential (TRAP), Trolox equivalent antioxidant capacity (TEAC), and ferric reducing ability of plasma (FRAP). Anthropometric parameters (body mass index and waist circumference), were investigated using standard methods. Results: After adjustment for possible covariates, both TRAP and TEAC were significantly positively associated with obesity (TRAP: OR, 1.65; 95% confidence interval [CI], 1.04–2.63; Ptrend, 0.03; TEAC: OR, 1.63; 95% CI, 1.01–2.63; Ptrend, 0.04). However, there was no association between FRAP and obesity (OR, 1.11; 95% CI, 0.64–1.93; Ptrend, 0.68). Moreover, no relationship was found between different DTAC indices and waist circumference (TRAP: OR, 1.13; 95% CI, 0.70–1.80; Ptrend, 0.60; TEAC: OR, 1.04; 95% CI, 0.64–1.69; Ptrend, 0.87; FRAP: OR, 0.86; 95% CI, 0.49–1.51; Ptrend, 0.62). Conclusion: Women with higher DTAC scores had higher risk for obesity. No association was found between DTAC and waist circumference.
AB - Objectives: Reactive oxygen species level is a fundamental component in the pathogenesis of obesity that might be reduced by dietary antioxidants. Measurement of dietary total antioxidant capacity (DTAC) is regarded as a new holistic dietary index. Given the limited research on DTAC, the aim of this study was to examine the association of DTAC with obesity-related features in women. Methods: The present cross-sectional study included 627 female participants. Data on dietary intake were assessed using a validated food frequency questionnaire. DTAC was estimated through total reactive antioxidant potential (TRAP), Trolox equivalent antioxidant capacity (TEAC), and ferric reducing ability of plasma (FRAP). Anthropometric parameters (body mass index and waist circumference), were investigated using standard methods. Results: After adjustment for possible covariates, both TRAP and TEAC were significantly positively associated with obesity (TRAP: OR, 1.65; 95% confidence interval [CI], 1.04–2.63; Ptrend, 0.03; TEAC: OR, 1.63; 95% CI, 1.01–2.63; Ptrend, 0.04). However, there was no association between FRAP and obesity (OR, 1.11; 95% CI, 0.64–1.93; Ptrend, 0.68). Moreover, no relationship was found between different DTAC indices and waist circumference (TRAP: OR, 1.13; 95% CI, 0.70–1.80; Ptrend, 0.60; TEAC: OR, 1.04; 95% CI, 0.64–1.69; Ptrend, 0.87; FRAP: OR, 0.86; 95% CI, 0.49–1.51; Ptrend, 0.62). Conclusion: Women with higher DTAC scores had higher risk for obesity. No association was found between DTAC and waist circumference.
KW - Body mass index
KW - Ferric reducing ability of plasma
KW - Total reactive antioxidant potential
KW - Trolox equivalent antioxidant capacity
KW - Waist circumference
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U2 - 10.1016/j.nut.2019.110577
DO - 10.1016/j.nut.2019.110577
M3 - Article
C2 - 31610483
AN - SCOPUS:85073071535
SN - 0899-9007
VL - 69
JO - Nutrition
JF - Nutrition
M1 - 110577
ER -