Association of cadmium with diabetes in middle-aged residents of abandoned metal mines: The first health effect surveillance for residents in abandoned metal mines

Hee Seung Son, Soo Geun Kim, Byung Seong Suh, Dong Uk Park, Dae Seon Kim, Seung Do Yu, Yeong Seoub Hong, Jung Duck Park, Byung Kook Lee, Jai Dong Moon, Joon Sakong

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: The aim of this study was to determine the association between urinary cadmium (U-cd) concentration and diabetes in middle-aged Korean residents of abandoned mines using the first Health Effect Surveillance for Residents in Abandoned Metal mines (HESRAM). Methods: This study was cross-sectional study conducted on 719 residents between 40-70 years in 38 abandoned metal mines in Korea. Data was collected by HESRAM from 2008 to 2011. The correlation coefficient of U-cd and fasting blood glucose, odds ratio in urinary cadmium tertiles and diabetes prevalence was analyzed according to the sex category. Results: The correlation coefficient U-cd concentration and fasting blood glucose was 0.182 in male. Logistic regression analysis in male revealed a third tertile odds ratio of U-cd (2 μg/g creatinine < U-cd) while diabetes prevalence was 1.81 (95 % CI 1.05-3.12) with adjusted age, BMI, smoking and alcohol consumption, region, family income. On the other hand, the odds ratio for third tertile of U-cd (3 μg/g creatinine < U-cd) between diabetes prevalence in female was 1.39 (95 % CI 0.52-3.72) in addition to adjusted menopausal status. Conclusions: Environmental exposure to cadmium in abandoned mine residents was associated with diabetes in male. Closed monitoring and periodic evaluation of the health effects of chronic environmental exposure on abandoned mines residents will be needed.

Original languageEnglish (US)
Article number20
JournalAnnals of Occupational and Environmental Medicine
Volume27
Issue number1
DOIs
StatePublished - 2015

Keywords

  • Abandoned mine
  • Diabetes
  • Environmental disorder
  • Glucose
  • Urine cadmium

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

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