Abstract
Purpose. To determine the relationship between aspects of vision and health-related quality-of-life (QoL) among patients with subfoveal choroidal neovascularization (CNV) in at least one eye who are enrolled in the Submacular Surgery Trials (SST) Pilot Study. Methods. Using multivariate linear regression models, measures of vision from the better eye of 271 patients enrolled in the SST were assessed for their contributions to QoL measured using the physical (PCS) and mental (MCS) summary scales from the SF-36 administered during baseline in-person interviews. Results, Overall age- and gender- specific PCS and MCS scores in these patients were similar to published norms. After adjustment for demographic factors: better visual acuity was significantly (p <.05) associated with higher PCS and MCS scores; better contrast sensitivity was marginally (.05 <p <.10) related to both summary scales; and higher reading speed was significantly related to higher MCS scores but not PCS scores. Taken together, the three vision measures in both eyes explained 4.5% and 6.8% of the total variation in MCS and PCS scales, respectively. Conclusions. This widely-used questionnaire for assessing QoL is responsive to the three components of vision being measured in patients enrolled in the SST who represent a wide range of ages, have variations in co-morbidities, and have impaired vision in one eye and often both eyes.
| Original language | English (US) |
|---|---|
| Journal | Investigative Ophthalmology and Visual Science |
| Volume | 38 |
| Issue number | 4 |
| State | Published - 1997 |
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ASJC Scopus subject areas
- Ophthalmology
Cite this
Association of aspects of vision and quality-of-life in patients with subfoveal choroidal neovascularization. / Gange, Stephen J; Marsh, M.
In: Investigative Ophthalmology and Visual Science, Vol. 38, No. 4, 1997.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Association of aspects of vision and quality-of-life in patients with subfoveal choroidal neovascularization
AU - Gange, Stephen J
AU - Marsh, M.
PY - 1997
Y1 - 1997
N2 - Purpose. To determine the relationship between aspects of vision and health-related quality-of-life (QoL) among patients with subfoveal choroidal neovascularization (CNV) in at least one eye who are enrolled in the Submacular Surgery Trials (SST) Pilot Study. Methods. Using multivariate linear regression models, measures of vision from the better eye of 271 patients enrolled in the SST were assessed for their contributions to QoL measured using the physical (PCS) and mental (MCS) summary scales from the SF-36 administered during baseline in-person interviews. Results, Overall age- and gender- specific PCS and MCS scores in these patients were similar to published norms. After adjustment for demographic factors: better visual acuity was significantly (p <.05) associated with higher PCS and MCS scores; better contrast sensitivity was marginally (.05
AB - Purpose. To determine the relationship between aspects of vision and health-related quality-of-life (QoL) among patients with subfoveal choroidal neovascularization (CNV) in at least one eye who are enrolled in the Submacular Surgery Trials (SST) Pilot Study. Methods. Using multivariate linear regression models, measures of vision from the better eye of 271 patients enrolled in the SST were assessed for their contributions to QoL measured using the physical (PCS) and mental (MCS) summary scales from the SF-36 administered during baseline in-person interviews. Results, Overall age- and gender- specific PCS and MCS scores in these patients were similar to published norms. After adjustment for demographic factors: better visual acuity was significantly (p <.05) associated with higher PCS and MCS scores; better contrast sensitivity was marginally (.05
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M3 - Article
AN - SCOPUS:33749216247
VL - 38
JO - Investigative Ophthalmology and Visual Science
JF - Investigative Ophthalmology and Visual Science
SN - 0146-0404
IS - 4
ER -