Association between the Dopamine Receptor D5 Gene and the Liability to Substance Dependence in Males: A Replication

Michael M. Vanyukov; Brion S. Maher; Robert E. Ferrell; Bernard Devlin; Mary L. Marazita; Galina P. Kirillova

doi:10.1300/J029v10n04_06

Association between the Dopamine Receptor D5 Gene and the Liability to Substance Dependence in Males: A Replication

Michael M. Vanyukov, Brion S. Maher, Robert E. Ferrell, Bernard Devlin, Mary L. Marazita, Galina P. Kirillova

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

The heritability of substance dependence (SD) liability is based on polymorphisms at the genes that are likely to be related to the function of the central nervous system. We have recently shown an association between the dopamine D5 receptor gene and SD liability. We report herein a replication of this association in an independent case-control sample.

Original language	English (US)
Pages (from-to)	55-63
Number of pages	9
Journal	Journal of Child and Adolescent Substance Abuse
Volume	10
Issue number	4
DOIs	https://doi.org/10.1300/J029v10n04_06
State	Published - 2001
Externally published	Yes

Keywords

Candidate gene
Complex traits
DRD5 gene
Drug abuse
Quantitative trait
Severity

ASJC Scopus subject areas

Social Psychology
Education
General Psychology
Public Health, Environmental and Occupational Health

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10.1300/J029v10n04_06

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abstract = "The heritability of substance dependence (SD) liability is based on polymorphisms at the genes that are likely to be related to the function of the central nervous system. We have recently shown an association between the dopamine D5 receptor gene and SD liability. We report herein a replication of this association in an independent case-control sample.",

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AU - Maher, Brion S.

AU - Ferrell, Robert E.

AU - Devlin, Bernard

AU - Marazita, Mary L.

AU - Kirillova, Galina P.

PY - 2001

Y1 - 2001

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AB - The heritability of substance dependence (SD) liability is based on polymorphisms at the genes that are likely to be related to the function of the central nervous system. We have recently shown an association between the dopamine D5 receptor gene and SD liability. We report herein a replication of this association in an independent case-control sample.

KW - Candidate gene

KW - Complex traits

KW - DRD5 gene

KW - Drug abuse

KW - Quantitative trait

KW - Severity

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Association between the Dopamine Receptor D5 Gene and the Liability to Substance Dependence in Males: A Replication

Abstract

Keywords

ASJC Scopus subject areas

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