Association between the Dopamine Receptor D5 Gene and the Liability to Substance Dependence in Males: A Replication

Michael M. Vanyukov, Brion Maher, Robert E. Ferrell, Bernard Devlin, Mary L. Marazita, Galina P. Kirillova

Research output: Contribution to journalArticle

Abstract

The heritability of substance dependence (SD) liability is based on polymorphisms at the genes that are likely to be related to the function of the central nervous system. We have recently shown an association between the dopamine D5 receptor gene and SD liability. We report herein a replication of this association in an independent case-control sample.

Original languageEnglish (US)
Pages (from-to)55-63
Number of pages9
JournalJournal of Child and Adolescent Substance Abuse
Volume10
Issue number4
DOIs
StatePublished - 2001
Externally publishedYes

Fingerprint

Dopamine D5 Receptors
liability
Substance-Related Disorders
gene
heritability
nervous system
Genes
polymorphism
Central Nervous System

Keywords

  • Candidate gene
  • Complex traits
  • DRD5 gene
  • Drug abuse
  • Quantitative trait
  • Severity

ASJC Scopus subject areas

  • Development
  • Social Psychology
  • Psychology(all)
  • Public Health, Environmental and Occupational Health

Cite this

Association between the Dopamine Receptor D5 Gene and the Liability to Substance Dependence in Males : A Replication. / Vanyukov, Michael M.; Maher, Brion; Ferrell, Robert E.; Devlin, Bernard; Marazita, Mary L.; Kirillova, Galina P.

In: Journal of Child and Adolescent Substance Abuse, Vol. 10, No. 4, 2001, p. 55-63.

Research output: Contribution to journalArticle

Vanyukov, Michael M. ; Maher, Brion ; Ferrell, Robert E. ; Devlin, Bernard ; Marazita, Mary L. ; Kirillova, Galina P. / Association between the Dopamine Receptor D5 Gene and the Liability to Substance Dependence in Males : A Replication. In: Journal of Child and Adolescent Substance Abuse. 2001 ; Vol. 10, No. 4. pp. 55-63.
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