Association between semen exposure and incident bacterial vaginosis

Maria F. Gallo, Lee Warner, Caroline C. King, Jack D. Sobel, Robert S. Klein, Susan Cu-Uvin, Anne Marie Rompalo, Denise J. Jamieson

Research output: Contribution to journalArticle

Abstract

Objective. To identify correlates of incident bacterial vaginosis (BV) diagnosed with Nugent scoring among high-risk women. Study Design. We conducted both cohort and case-crossover analyses, stratified by HIV infection status, based on 871 HIV-infected and 439 HIV-uninfected participants in the HIV Epidemiology Research Study, conducted in 4 US sites in 1993-2000. Results. BV incidence was 21 and 19 among HIV-infected and -uninfected women, respectively. Fewer correlates of BV were found with case-crossover than with cohort design. Reporting frequent coitus (regardless of consistency of condom use) was correlated with BV in cohort analyses but not in case-crossover analyses. The sole correlate of BV in both types of analyses was the detection of spermatozoa on Gram stain, which is a marker of semen exposure. Conclusion. The inconsistent association between condom use and BV in prior studies could be from reporting bias. We found evidence of a relationship between semen exposure and incident BV.

Original languageEnglish (US)
Article number842652
JournalInfectious Diseases in Obstetrics and Gynecology
Volume2011
DOIs
StatePublished - 2011

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Bacterial Vaginosis
Semen
HIV
Condoms
HIV Infections
Spermatozoa
Epidemiology
Cohort Studies
Incidence
Research

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Infectious Diseases
  • Dermatology

Cite this

Gallo, M. F., Warner, L., King, C. C., Sobel, J. D., Klein, R. S., Cu-Uvin, S., ... Jamieson, D. J. (2011). Association between semen exposure and incident bacterial vaginosis. Infectious Diseases in Obstetrics and Gynecology, 2011, [842652]. https://doi.org/10.1155/2011/842652

Association between semen exposure and incident bacterial vaginosis. / Gallo, Maria F.; Warner, Lee; King, Caroline C.; Sobel, Jack D.; Klein, Robert S.; Cu-Uvin, Susan; Rompalo, Anne Marie; Jamieson, Denise J.

In: Infectious Diseases in Obstetrics and Gynecology, Vol. 2011, 842652, 2011.

Research output: Contribution to journalArticle

Gallo, MF, Warner, L, King, CC, Sobel, JD, Klein, RS, Cu-Uvin, S, Rompalo, AM & Jamieson, DJ 2011, 'Association between semen exposure and incident bacterial vaginosis', Infectious Diseases in Obstetrics and Gynecology, vol. 2011, 842652. https://doi.org/10.1155/2011/842652
Gallo, Maria F. ; Warner, Lee ; King, Caroline C. ; Sobel, Jack D. ; Klein, Robert S. ; Cu-Uvin, Susan ; Rompalo, Anne Marie ; Jamieson, Denise J. / Association between semen exposure and incident bacterial vaginosis. In: Infectious Diseases in Obstetrics and Gynecology. 2011 ; Vol. 2011.
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AU - Rompalo, Anne Marie

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