Association between physical and cognitive function in healthy elderly

The health, aging and body composition study

Caterina Rosano, Eleanor Marie Simonsick, Tamara B. Harris, Steven B. Kritchevsky, Jennifer Brach, Marjolein Visser, Kristine Yaffe, Anne B. Newman

Research output: Contribution to journalArticle

Abstract

Performance measures of physical function (gait speed, chair stands, standing balance) and cognitive function [Teng-modified Mini-Mental Status Exam (3MS) and digit symbol substitution test (DSST)] were assessed at baseline in 3,075 participants in the Health, Aging and Body Composition Study. Each physical function measure was examined for the strength and magnitude of association with cognitive function. All physical function measures were associated with both the 3MS and DSST scores (p <0.001), and in multivariate analysis each relationship was independent of demographic characteristics, weight, physical activity and comorbid health conditions of participants. The association of motor performance was consistently greater for the DSST than the 3MS and, among the motor tests, gait speed retained a significant association with both cognitive measures independent of demographic, weight, physical activity and comorbid health conditions. In this large cohort of high-functioning older adults, the correlation between physical and cognitive function was not entirely explained by demographics. Longitudinal studies are needed to determine the direction of causality in this relationship.

Original languageEnglish (US)
Pages (from-to)8-14
Number of pages7
JournalNeuroepidemiology
Volume24
Issue number1-2
DOIs
StatePublished - 2005
Externally publishedYes

Fingerprint

Body Composition
Cognition
Demography
Health
Exercise
Weights and Measures
Causality
Longitudinal Studies
Multivariate Analysis
Walking Speed

Keywords

  • Cognitive performance
  • Gait speed
  • Physical function
  • Well-functioning elderly

ASJC Scopus subject areas

  • Epidemiology
  • Clinical Neurology

Cite this

Association between physical and cognitive function in healthy elderly : The health, aging and body composition study. / Rosano, Caterina; Simonsick, Eleanor Marie; Harris, Tamara B.; Kritchevsky, Steven B.; Brach, Jennifer; Visser, Marjolein; Yaffe, Kristine; Newman, Anne B.

In: Neuroepidemiology, Vol. 24, No. 1-2, 2005, p. 8-14.

Research output: Contribution to journalArticle

Rosano, C, Simonsick, EM, Harris, TB, Kritchevsky, SB, Brach, J, Visser, M, Yaffe, K & Newman, AB 2005, 'Association between physical and cognitive function in healthy elderly: The health, aging and body composition study', Neuroepidemiology, vol. 24, no. 1-2, pp. 8-14. https://doi.org/10.1159/000081043
Rosano, Caterina ; Simonsick, Eleanor Marie ; Harris, Tamara B. ; Kritchevsky, Steven B. ; Brach, Jennifer ; Visser, Marjolein ; Yaffe, Kristine ; Newman, Anne B. / Association between physical and cognitive function in healthy elderly : The health, aging and body composition study. In: Neuroepidemiology. 2005 ; Vol. 24, No. 1-2. pp. 8-14.
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