TY - JOUR
T1 - Association between obesity and chronic obstructive pulmonary disease in Moroccan adults
T2 - Evidence from the BOLD study
AU - Benslimane, Abdelilah
AU - Garcia-Larsen, Vanessa
AU - El Kinany, Khaoula
AU - Alaoui Chrifi, Amina
AU - Hatime, Zineb
AU - Benjelloun, Mohamed Chakib
AU - El Biaze, Mohammed
AU - Nejjari, Chakib
AU - El Rhazi, Karima
N1 - Funding Information:
Many thanks to all contributors to this work in the University Hospital center of Fez city and to the BOLD team in the Imperial College of London, UK. Moreover, many thanks to Ghada A. Soliman, MD, PhD, for her contributions to the manuscript revision. The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: Many thanks to Boehringer Laboratory-Morocco (Fez, Morocco) and Welcome Grant No. 085790/Z/08/Z for the financing of this study.
Funding Information:
The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: Many thanks to Boehringer Laboratory-Morocco (Fez, Morocco) and Welcome Grant No. 085790/Z/08/Z for the financing of this study.
Publisher Copyright:
© The Author(s) 2021.
PY - 2021
Y1 - 2021
N2 - Objective: The Moroccan cross-sectional study aimed to investigate obesity in association to chronic obstructive pulmonary disease in Fez city. Methods: A cross-sectional survey was carried out in Moroccan adults. Anthropometric and spirometry measurements were performed using standardized guidelines. Results: Among the 744 participants, 53.9% of were women, with a mean age of 55.27 years (SD = 10.29). Nearly all women declared themselves to be never smokers, while 21% of men were current smokers. Overall, chronic obstructive pulmonary disease prevalence decreased with body mass index (p = 0.01) and waist circumference (p < 0.001). The same trends were also observed in women. The adjusted regression analysis showed a significant independent association between chronic obstructive pulmonary disease and decreasing overweight (ORa: 0.66; CI95% (0.40–0.98)), obesity (ORa: 0.66 CI95%: (0.36–0.89)), and a decreasing waist circumference-abdominal obesity (ORa: 0.58 CI95%: (0.34–0.99)) in the whole population. The same association remains significant in women for overweight (ORa: 0.18 CI95%: (0.06–0.54)) and for waist circumference-abdominal obesity (ORa: 0.40 CI95%: (0.19–0.85)). All these associations disappeared for men. Conclusion: Chronic obstructive pulmonary disease decreases with the increase in body mass index and waist circumference. The effect of waist circumference on the chronic obstructive pulmonary disease was greater among women, regardless of the tobacco factor. A multicenter study would help to confirm the accuracy of these findings in a larger sample of the Moroccan population. Developed lifestyle programs in patients with chronic obstructive pulmonary disease should be considered.
AB - Objective: The Moroccan cross-sectional study aimed to investigate obesity in association to chronic obstructive pulmonary disease in Fez city. Methods: A cross-sectional survey was carried out in Moroccan adults. Anthropometric and spirometry measurements were performed using standardized guidelines. Results: Among the 744 participants, 53.9% of were women, with a mean age of 55.27 years (SD = 10.29). Nearly all women declared themselves to be never smokers, while 21% of men were current smokers. Overall, chronic obstructive pulmonary disease prevalence decreased with body mass index (p = 0.01) and waist circumference (p < 0.001). The same trends were also observed in women. The adjusted regression analysis showed a significant independent association between chronic obstructive pulmonary disease and decreasing overweight (ORa: 0.66; CI95% (0.40–0.98)), obesity (ORa: 0.66 CI95%: (0.36–0.89)), and a decreasing waist circumference-abdominal obesity (ORa: 0.58 CI95%: (0.34–0.99)) in the whole population. The same association remains significant in women for overweight (ORa: 0.18 CI95%: (0.06–0.54)) and for waist circumference-abdominal obesity (ORa: 0.40 CI95%: (0.19–0.85)). All these associations disappeared for men. Conclusion: Chronic obstructive pulmonary disease decreases with the increase in body mass index and waist circumference. The effect of waist circumference on the chronic obstructive pulmonary disease was greater among women, regardless of the tobacco factor. A multicenter study would help to confirm the accuracy of these findings in a larger sample of the Moroccan population. Developed lifestyle programs in patients with chronic obstructive pulmonary disease should be considered.
KW - BOLD study
KW - Morocco
KW - abdominal obesity
KW - chronic obstructive pulmonary disease
KW - obesity
UR - http://www.scopus.com/inward/record.url?scp=85110431058&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85110431058&partnerID=8YFLogxK
U2 - 10.1177/20503121211031428
DO - 10.1177/20503121211031428
M3 - Article
C2 - 34349996
AN - SCOPUS:85110431058
SN - 2050-3121
VL - 9
JO - SAGE Open Medicine
JF - SAGE Open Medicine
ER -