TY - JOUR
T1 - Association Between Adherence to the Mediterranean Diet and Asthma in Peruvian Children
AU - Rice, Jessica L.
AU - Romero, Karina M.
AU - Galvez Davila, Rocio M.
AU - Meza, Carla Tarazona
AU - Bilderback, Andrew
AU - Williams, D. Ann L.
AU - Breysse, Patrick N.
AU - Bose, Sonali
AU - Checkley, William
AU - Hansel, Nadia N.
N1 - Funding Information:
We would like to acknowledge study investigators and staff of the Genetic susceptibility to Asthma and pollution in Peru (GASP) Study: Patrick N. Breysse, William Checkley, Rocio M. Galvez Davila, Gregory B Diette, Rafael Guerrero-Preston, Nadia N. Hansel, Caroline Johnson, John Lima, Gary Malpartida, Ed Mougey, Jesse Negherbon, Suzanne Pollard, Karina M. Romero, Carla Tarazona, Lindsay Underhill, D’Ann L. Williams. The Genetic susceptibility to Asthma and pollution in Peru (GASP) Study was supported by NIEHS R01ES018845.
Publisher Copyright:
© 2015, The Author(s).
PY - 2015/12/1
Y1 - 2015/12/1
N2 - Purpose: Adherence to a Mediterranean diet pattern may be associated with lower asthma prevalence in children. We sought to corroborate these findings in Peruvian children. Methods: This case–control study included children of ages 9–19 years living in Lima, Peru. A food frequency questionnaire (FFQ) was completed and diet pattern was analyzed using a modified Mediterranean diet score (MDS). Primary analysis investigated the relationship between MDS and asthma status. Maternal education, age, sex, and body mass index category were included in multivariate model. Secondary outcomes included asthma control, forced expiratory volume in 1 s (FEV1), allergic rhinitis, and atopic status. Results: 287 participants with asthma and 96 controls without asthma completed a FFQ. Mean age was 13.5 years. According to the asthma control test (ACT), 86 % of those with asthma were controlled (score >19). MDS scores ranged 6–18 (median 15). In adjusted analysis, being above the median MDS scores was associated with decreased odds of asthma [OR = 0.55, 95 % CI (0.33, 0.92), p = 0.02]. Among children whose mothers completed secondary education, being above the median MDS significantly decreased the odds of asthma [OR = 0.31, 95 % CI (0.14, 0.71), p < 0.01], whereas among those whose mothers did not complete secondary education there was no protective effect [OR = 0.86, 95 % CI (0.43, 1.7), p = 0.66]. There was no association between MDS scores and asthma control, FEV1, allergic rhinitis, or atopic status. Conclusion: Adherence to the Mediterranean diet was inversely associated with having asthma among children in Lima, Peru. This effect was strongest among children with better educated mothers.
AB - Purpose: Adherence to a Mediterranean diet pattern may be associated with lower asthma prevalence in children. We sought to corroborate these findings in Peruvian children. Methods: This case–control study included children of ages 9–19 years living in Lima, Peru. A food frequency questionnaire (FFQ) was completed and diet pattern was analyzed using a modified Mediterranean diet score (MDS). Primary analysis investigated the relationship between MDS and asthma status. Maternal education, age, sex, and body mass index category were included in multivariate model. Secondary outcomes included asthma control, forced expiratory volume in 1 s (FEV1), allergic rhinitis, and atopic status. Results: 287 participants with asthma and 96 controls without asthma completed a FFQ. Mean age was 13.5 years. According to the asthma control test (ACT), 86 % of those with asthma were controlled (score >19). MDS scores ranged 6–18 (median 15). In adjusted analysis, being above the median MDS scores was associated with decreased odds of asthma [OR = 0.55, 95 % CI (0.33, 0.92), p = 0.02]. Among children whose mothers completed secondary education, being above the median MDS significantly decreased the odds of asthma [OR = 0.31, 95 % CI (0.14, 0.71), p < 0.01], whereas among those whose mothers did not complete secondary education there was no protective effect [OR = 0.86, 95 % CI (0.43, 1.7), p = 0.66]. There was no association between MDS scores and asthma control, FEV1, allergic rhinitis, or atopic status. Conclusion: Adherence to the Mediterranean diet was inversely associated with having asthma among children in Lima, Peru. This effect was strongest among children with better educated mothers.
KW - Allergic rhinitis
KW - Atopic
KW - Control
KW - Diet pattern
KW - Food frequency questionnaire
KW - Peru
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U2 - 10.1007/s00408-015-9792-9
DO - 10.1007/s00408-015-9792-9
M3 - Article
C2 - 26335393
AN - SCOPUS:84947494748
VL - 193
SP - 893
EP - 899
JO - Pneumonologie. Pneumonology
JF - Pneumonologie. Pneumonology
SN - 0341-2040
IS - 6
ER -