Assiociations of patella lead with polymorphisms in the vitamin D receptor, δ-aminolevulinic acid dehydratase and endothelial nitric oxide synthase genes

Keson Theppeang, Brian S Schwartz, Byung Kook Lee, Mark E. Lustberg, Ellen Silbergeld, Karl T. Kelsey, Patrick J. Parsons, Andrew C. Todd

Research output: Contribution to journalArticle

Abstract

A cross-sectional analysis was performed to evaluate associations of polymorphisms in the vitamin D receptor (VDR), δ-aminolevulinic acid dehydratase (ALAD), and endothelial nitric oxide synthase (eNOS) genes with patella lead concentrations in 652 lead workers in the Republic of Korea. There was a wide range of patella lead (from below detection limit to 946 μg Pb/g bone mineral), with a mean (standard deviation) of 75.2 (101.0). There were no associations of ALAD or eNOS genotypes with patella lead, but workers with the VDR B allele had significantly (P value

Original languageEnglish (US)
Pages (from-to)528-537
Number of pages10
JournalJournal of Occupational and Environmental Medicine
Volume46
Issue number6
DOIs
StatePublished - Jun 2004

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ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis

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