Assessment of ventricular contractility during cardiac magnetic resonance imaging examinations using normalized maximal ventricular power

Randy M. Setser, Kay Sayre, Sebastian Flacke, Jon Chia, Kamilla Lunn, Christine H. Lorenz

Research output: Contribution to journalArticlepeer-review

Abstract

Normalized maximal ventricular power was analyzed in humans using magnetic resonance imaging (MRI) measurements with aortic pressure. The sensitivity of the power was tested to left ventricle contractility with dobutamine and to cardiac loading with methoxamine. It was found that aortic pressures can be estimated using a transfer function, generated and validated in a group of patients undergoing cardiac catheterization. Results also showed that ventricular contractility can be assessed independent of cardiac loading in patients during cardiac imaging.

Original languageEnglish (US)
Pages (from-to)974-982
Number of pages9
JournalAnnals of Biomedical Engineering
Volume29
Issue number11
DOIs
StatePublished - 2001
Externally publishedYes

Keywords

  • Afterload
  • Contractility
  • Dobutamine
  • Inotropic stimulation
  • Left ventricle
  • MRI
  • Preload

ASJC Scopus subject areas

  • Biomedical Engineering

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