Assessment of regional myocardial strain using cardiac elastography: Distinguishing infarcted from non-infarcted myocardium

Elisa E. Konofagou, Timothy Harrigan, Scott Solomon

Research output: Contribution to journalArticle

Abstract

Estimation of the regional mechanical properties of the cardiac muscle has been shown to play a crucial role in the detection of cardiovascular disease. Current echocardiography-based cardiac motion estimation techniques, such as Doppler Myocardial Imaging (DMI), are limited due to angle dependence. By contrast, elastography, a method designed and used for the detection of tumors, measures displacement and strain by comparing echoes before and after (not during) a deformation and thus is not angle-dependent. Therefore, the feasibility of cardiac elastography to provide reliable and reproducible displacement and strain estimates from multiple sonographic views was recently demonstrated utilizing RF data from a normal human heart in vivo [1]. In this paper, we demonstrate this technique utilizing 2D B-scan data in a patient with a known myocardial infarction. Envelope-detected sonographic data was used to estimate regional wall motion and deformation. Displacement and strain estimates were obtained in both non-infarcted, normally contracting and infarcted regions. By obtaining ciné-loop and M-Mode elastograms from both regions, the ischemic regions could be identified. In conclusion, elastography may be a clinically viable method for detection of abnormalities of regional wall motion throughout the cardiac cycle.

Original languageEnglish (US)
Pages (from-to)1589-1592
Number of pages4
JournalProceedings of the IEEE Ultrasonics Symposium
Volume2
DOIs
StatePublished - Jan 1 2001
Externally publishedYes

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

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