Assessment of myocardial fibrosis with cardiovascular magnetic resonance

Nathan Mewton, Chia Ying Liu, Pierre Croisille, David Bluemke, Joo A.C. Lima

Research output: Contribution to journalReview article

Abstract

Diffuse interstitial or replacement myocardial fibrosis is a common feature of a broad variety of cardiomyopathies. Myocardial fibrosis leads to impaired cardiac diastolic and systolic function and is related to adverse cardiovascular events. Cardiovascular magnetic resonance (CMR) may uniquely characterize the extent of replacement fibrosis and may have prognostic value in various cardiomyopathies. Myocardial longitudinal relaxation time mapping is an emerging technique that could improve CMR's diagnostic accuracy, especially for interstitial diffuse myocardial fibrosis. As such, CMR could be integrated in the monitoring and therapeutic management of a large number of patients. This review summarizes the advantages and limitations of CMR for the assessment of myocardial fibrosis.

Original languageEnglish (US)
Pages (from-to)891-903
Number of pages13
JournalJournal of the American College of Cardiology
Volume57
Issue number8
DOIs
StatePublished - Feb 22 2011

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Keywords

  • T1 mapping
  • cardiac magnetic resonance
  • late gadolinium enhancement
  • myocardial fibrosis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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