Assessment of myocardial deformation in children using digital imaging and communications in medicine (DICOM) data and vendor independent speckle tracking software

Laurens P. Koopman, Cameron Slorach, Cedric Manlhiot, Brian W. McCrindle, Edgar T. Jaeggi, Luc Mertens, Mark K. Friedberg

Research output: Contribution to journalArticle


Background: Analysis of myocardial deformation from data stored in Digital Imaging and Communications in Medicine format using vendor-independent software may be useful for clinical and research purposes but has not been evaluated in children. Methods: Grayscale images were prospectively acquired on Vivid 7 (GE Healthcare) and iE33 (Philips Medical Systems) ultrasound systems in 49 children. Digital Imaging and Communications in Medicine and raw data were analyzed using vendor-independent software (Cardiac Performance Analysis, Tomtec Imaging Systems) and vendor-specific software (EchoPAC and QLAB) and results compared. In addition, vendor-independent software using images at 30 frames/sec were compared with images at the higher acquisition frame rate. Results: Measurement of short-axis radial and circumferential strain (ε) and apical four-chamber longitudinal ε by vendor-independent software was possible in >92% of the children. Intraobserver and interobserver coefficients of variation for global circumferential and longitudinal ε ranged from 7.1% to 15.3% and for radial ε from 23.9% to 30.2%. Strain values were somewhat higher when using GE images at acquisition frame rates compared with ε values using GE images stored at 30 frames/sec. Strain values obtained by vendor-independent software were comparable with those obtained by vendor-specific software for longitudinal ε and higher for circumferential ε. Radial ε values obtained by vendor-independent software were lower than ε values by EchoPAC and higher than ε values by QLAB. Conclusions: Vendor-independent software-derived ε is feasible and potentially valuable for measuring myocardial deformation in research and in multicenter studies using images from different ultrasound systems, especially for longitudinal deformation. However, a systematic bias for circumferential ε and a high variability in radial ε measurements remain concerns.

Original languageEnglish (US)
Pages (from-to)37-44
Number of pages8
JournalJournal of the American Society of Echocardiography
Issue number1
StatePublished - Jan 1 2011
Externally publishedYes



  • Child
  • DICOM data
  • Myocardial deformation
  • Vendor-independent software

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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