Assessment of electrical burn injury using structured illumination in an in vivo electrical injury model

Thu T A Nguyen, Ali Basiri, J. W. Shupp, L. T. Moffatt, M. H. Jordan, J. C. Jeng, E. Leto, J. C. Ramella-Roman

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Electrical injury is a devastating and hard to treat clinical lesion. Fully understanding the pathophysiology of electrical trauma is still a challenge for clinicians and scientists. Further elucidating the natural history of this form of tissue injury could be helpful in improving limb salvage and offering stage-appropriate therapy. Multi-spectral imaging technique is a non-invasive technology that can be used to determine optical properties of tissues in and adjacent to injury. Images at different wavelengths can provide essential information related to the pathophysiological condition of the tissue. To promote the applicability of this technique in medical diagnosis, we built a complete experimental model of electrical injury. In this model, electrical injuries were created by a reliable high-tension shock system at preset voltage or current. A thermal camera recorded the change of skin temperature during the electrical shock. Then, a high-resolution spectral imaging system based on structured illumination was used to capture images for post analysis to extrapolate optical properties of the tissue. To test accuracy, this imaging system was calibrated by using a set of epoxy phantoms with known optical properties. In this paper, the results of experiments conducted on rats and discussions on the systemic changes in tissue optical properties before and after electrical shock are presented.

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7999
DOIs
StatePublished - 2011
Externally publishedYes
EventSaratov Fall Meeting 2010: Optical Technologies in Biophysics and Medicine XII - Saratov, Russian Federation
Duration: Oct 5 2010Oct 8 2010

Other

OtherSaratov Fall Meeting 2010: Optical Technologies in Biophysics and Medicine XII
CountryRussian Federation
CitySaratov
Period10/5/1010/8/10

Keywords

  • Electrical burns
  • Spectral imaging

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Nguyen, T. T. A., Basiri, A., Shupp, J. W., Moffatt, L. T., Jordan, M. H., Jeng, J. C., Leto, E., & Ramella-Roman, J. C. (2011). Assessment of electrical burn injury using structured illumination in an in vivo electrical injury model. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 7999). [79990D] https://doi.org/10.1117/12.890313