Assessment of cutaneous innervation by skin biopsies

Research output: Contribution to journalReview articlepeer-review


Skin biopsies that are immunostained to identify nerve fibers provide a new tool for assessing the small caliber nociceptors that terminate in the epidermis, as well as other cutaneous nerve fibers. Skin biopsies can be performed in multiple sites and can be repeated over time, so that a spatiotemporal profile of epidermal innervation can be constructed. This approach may help assess the progression of fiber loss in disease and of regeneration and re-innervation with treatment.

Original languageEnglish (US)
Pages (from-to)655-659
Number of pages5
JournalCurrent opinion in neurology
Issue number5
StatePublished - Oct 24 2001

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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