Assessment of BNP and NT-proBNP in emergency department patients presenting with suspected acute coronary syndromes

Scott J. Cameron, Gary B. Green, C. Nicole White, Omar F. Laterza, William Clarke, Hong Kim, Lori J Sokoll

Research output: Contribution to journalArticle

Abstract

Objectives: The relationship between BNP and NT-proBNP among physiologically and clinically relevant demographic subgroups has never been clarified in the context of the emergency department (ED). Design and methods: A blood sample taken from patients presenting to the E.D. with suspected acute coronary syndromes (ACS) was analyzed for BNP and NT-proBNP, and correlation between them was examined as an entire group then as subgroups according to gender, ethnicity, age, and comorbidity variables. Results: BNP and NT-proBNP correlate well (0.89, P <0.0001) in a population of 420 patients and in patient subgroups with a history of various etiologies, including vascular disorders. Conclusions: In general, BNP and NT-proBNP correlate very well in patients with suspected ACS and may aid in the risk stratification process in emergency departments.

Original languageEnglish (US)
Pages (from-to)11-18
Number of pages8
JournalClinical Biochemistry
Volume39
Issue number1
DOIs
StatePublished - Jan 2006

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Acute Coronary Syndrome
Hospital Emergency Service
Blood Vessels
Comorbidity
Blood
Demography
pro-brain natriuretic peptide (1-76)
Population

Keywords

  • BNP
  • Chest pain
  • Correlation
  • Emergency department
  • NT-proBNP

ASJC Scopus subject areas

  • Clinical Biochemistry

Cite this

Assessment of BNP and NT-proBNP in emergency department patients presenting with suspected acute coronary syndromes. / Cameron, Scott J.; Green, Gary B.; White, C. Nicole; Laterza, Omar F.; Clarke, William; Kim, Hong; Sokoll, Lori J.

In: Clinical Biochemistry, Vol. 39, No. 1, 01.2006, p. 11-18.

Research output: Contribution to journalArticle

Cameron, Scott J. ; Green, Gary B. ; White, C. Nicole ; Laterza, Omar F. ; Clarke, William ; Kim, Hong ; Sokoll, Lori J. / Assessment of BNP and NT-proBNP in emergency department patients presenting with suspected acute coronary syndromes. In: Clinical Biochemistry. 2006 ; Vol. 39, No. 1. pp. 11-18.
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AB - Objectives: The relationship between BNP and NT-proBNP among physiologically and clinically relevant demographic subgroups has never been clarified in the context of the emergency department (ED). Design and methods: A blood sample taken from patients presenting to the E.D. with suspected acute coronary syndromes (ACS) was analyzed for BNP and NT-proBNP, and correlation between them was examined as an entire group then as subgroups according to gender, ethnicity, age, and comorbidity variables. Results: BNP and NT-proBNP correlate well (0.89, P <0.0001) in a population of 420 patients and in patient subgroups with a history of various etiologies, including vascular disorders. Conclusions: In general, BNP and NT-proBNP correlate very well in patients with suspected ACS and may aid in the risk stratification process in emergency departments.

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