Assessment of BNP and NT-proBNP in emergency department patients presenting with suspected acute coronary syndromes

Scott J. Cameron, Gary B. Green, C. Nicole White, Omar F. Laterza, William Clarke, Hong Kim, Lori J. Sokoll

Research output: Contribution to journalArticlepeer-review

Abstract

Objectives: The relationship between BNP and NT-proBNP among physiologically and clinically relevant demographic subgroups has never been clarified in the context of the emergency department (ED). Design and methods: A blood sample taken from patients presenting to the E.D. with suspected acute coronary syndromes (ACS) was analyzed for BNP and NT-proBNP, and correlation between them was examined as an entire group then as subgroups according to gender, ethnicity, age, and comorbidity variables. Results: BNP and NT-proBNP correlate well (0.89, P < 0.0001) in a population of 420 patients and in patient subgroups with a history of various etiologies, including vascular disorders. Conclusions: In general, BNP and NT-proBNP correlate very well in patients with suspected ACS and may aid in the risk stratification process in emergency departments.

Original languageEnglish (US)
Pages (from-to)11-18
Number of pages8
JournalClinical Biochemistry
Volume39
Issue number1
DOIs
StatePublished - Jan 1 2006

Keywords

  • BNP
  • Chest pain
  • Correlation
  • Emergency department
  • NT-proBNP

ASJC Scopus subject areas

  • Clinical Biochemistry

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