Assessing the impact of additional follow-up in cohort studies

Ron Brookmeyer, Nicholas Day, Vera Pompe-kirn

Research output: Contribution to journalArticlepeer-review

Abstract

An approach is described for predicting the statistical value of extending follow-up in a cohort study. A simple approximation to the expected number of new events of interest is given. The effect of these events an inferences for parameters such as a standardized mortality ratio is approached in two ways. The first concerns the probability of reversing the conclusion of a significance test. The second approach finds the plausible range of values for the standardized mortality ratio after further follow-up that are consistent with the currently available data. Each of these values is displayed together with the precision of the estimate. The methods are illustrated with results from the international Radiation Study of Cervical Cancer (IARC Scientific Publication No. 52, 1984).

Original languageEnglish (US)
Pages (from-to)611-619
Number of pages9
JournalAmerican journal of epidemiology
Volume121
Issue number4
DOIs
StatePublished - Apr 1985

Keywords

  • Biometry follow-up studies
  • Mortality
  • Radiation effects

ASJC Scopus subject areas

  • Epidemiology

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