Assessing the accuracy and precision of musculoskeletal motion tracking using cine-PC MRI on a 3.0T platform

Abrahm J. Behnam, Daniel A. Herzka, Frances T. Sheehan

Research output: Contribution to journalArticlepeer-review

42 Scopus citations


The rising cost of musculoskeletal pathology, disease, and injury creates a pressing need for accurate and reliable methods to quantify 3D musculoskeletal motion, fostering a renewed interest in this area over the past few years. To date, cine-phase contrast (PC) MRI remains the only technique capable of non-invasively tracking in vivo 3D musculoskeletal motion during volitional activity, but current scan times are long on the 1.5T MR platform (~2.5 min or 75 movement cycles). With the clinical availability of higher field strength magnets (3.0T) that have increased signal-to-noise ratios, it is likely that scan times can be reduced while improving accuracy. Therefore, the purpose of this study is to validate cine-PC MRI on a 3.0T platform, in terms of accuracy, precision, and subject-repeatability, and to determine if scan time could be minimized. On the 3.0T platform it is possible to limit scan time to 2 min, with sub-millimeter accuracy (<0.33 mm/0.97°), excellent technique precision (<0.18°), and strong subject-repeatability (<0.73 mm/1.10°). This represents reduction in imaging time by 25% (42 s), a 50% improvement in accuracy, and a 72% improvement in technique precision over the original 1.5T platform. Scan time can be reduced to 1 min (30 movement cycles), but the improvements in accuracy are not as large.

Original languageEnglish (US)
Pages (from-to)193-197
Number of pages5
JournalJournal of Biomechanics
Issue number1
StatePublished - Jan 4 2011
Externally publishedYes


  • Bone
  • Dynamic
  • Knee
  • Muscle
  • Patella
  • Phantom
  • Validation

ASJC Scopus subject areas

  • Biophysics
  • Orthopedics and Sports Medicine
  • Biomedical Engineering
  • Rehabilitation


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