TY - JOUR
T1 - Assessing the accuracy and precision of musculoskeletal motion tracking using cine-PC MRI on a 3.0T platform
AU - Behnam, Abrahm J.
AU - Herzka, Daniel A.
AU - Sheehan, Frances T.
N1 - Funding Information:
This research was supported by the Intramural Research Program of the NIH, and the Clinical Center at the NIH. We thank Sara Sadeghi, Bonnie Damaska, and the Diagnostic Radiology Department at the National Institutes of Health for their support and research time. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the authors and do not necessarily reflect the views of the National Institutes of Health or the US Public Health Service.
PY - 2011/1/4
Y1 - 2011/1/4
N2 - The rising cost of musculoskeletal pathology, disease, and injury creates a pressing need for accurate and reliable methods to quantify 3D musculoskeletal motion, fostering a renewed interest in this area over the past few years. To date, cine-phase contrast (PC) MRI remains the only technique capable of non-invasively tracking in vivo 3D musculoskeletal motion during volitional activity, but current scan times are long on the 1.5T MR platform (~2.5 min or 75 movement cycles). With the clinical availability of higher field strength magnets (3.0T) that have increased signal-to-noise ratios, it is likely that scan times can be reduced while improving accuracy. Therefore, the purpose of this study is to validate cine-PC MRI on a 3.0T platform, in terms of accuracy, precision, and subject-repeatability, and to determine if scan time could be minimized. On the 3.0T platform it is possible to limit scan time to 2 min, with sub-millimeter accuracy (<0.33 mm/0.97°), excellent technique precision (<0.18°), and strong subject-repeatability (<0.73 mm/1.10°). This represents reduction in imaging time by 25% (42 s), a 50% improvement in accuracy, and a 72% improvement in technique precision over the original 1.5T platform. Scan time can be reduced to 1 min (30 movement cycles), but the improvements in accuracy are not as large.
AB - The rising cost of musculoskeletal pathology, disease, and injury creates a pressing need for accurate and reliable methods to quantify 3D musculoskeletal motion, fostering a renewed interest in this area over the past few years. To date, cine-phase contrast (PC) MRI remains the only technique capable of non-invasively tracking in vivo 3D musculoskeletal motion during volitional activity, but current scan times are long on the 1.5T MR platform (~2.5 min or 75 movement cycles). With the clinical availability of higher field strength magnets (3.0T) that have increased signal-to-noise ratios, it is likely that scan times can be reduced while improving accuracy. Therefore, the purpose of this study is to validate cine-PC MRI on a 3.0T platform, in terms of accuracy, precision, and subject-repeatability, and to determine if scan time could be minimized. On the 3.0T platform it is possible to limit scan time to 2 min, with sub-millimeter accuracy (<0.33 mm/0.97°), excellent technique precision (<0.18°), and strong subject-repeatability (<0.73 mm/1.10°). This represents reduction in imaging time by 25% (42 s), a 50% improvement in accuracy, and a 72% improvement in technique precision over the original 1.5T platform. Scan time can be reduced to 1 min (30 movement cycles), but the improvements in accuracy are not as large.
KW - Bone
KW - Dynamic
KW - Knee
KW - Muscle
KW - Patella
KW - Phantom
KW - Validation
UR - http://www.scopus.com/inward/record.url?scp=78649981229&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78649981229&partnerID=8YFLogxK
U2 - 10.1016/j.jbiomech.2010.08.029
DO - 10.1016/j.jbiomech.2010.08.029
M3 - Article
C2 - 20863502
AN - SCOPUS:78649981229
VL - 44
SP - 193
EP - 197
JO - Journal of Biomechanics
JF - Journal of Biomechanics
SN - 0021-9290
IS - 1
ER -