Assessing pediatric tobacco exposure using parent report: comparison with hair nicotine

Judith A. Groner, Ana M Rule, Sharon A McGrath-Morrow, Michael Collaco, Angela Moss, Susanne E. Tanski, Robert McMillen, Regina M. Whitmore, Jonathan D. Klein, Jonathan P. Winickoff, Karen Wilson

Research output: Contribution to journalArticle

Abstract

Introduction: The purpose of this study was to examine the relationships between screening questions for secondhand smoke (SHS) exposure and biomarker results using hair nicotine levels. Our ultimate goal was to develop sensitive and valid screening tools in pediatric clinical settings for SHS exposure. Methods: Investigators developed a core set of questions regarding exposure. Data from two separate ongoing studies of well children and those with bronchopulmonary dysplasia (BPD) were used to assess the concordance between responses and hair nicotine levels. Sensitivity, a positive predictive value, and accuracy were examined. Results: There was no single question with similar sensitivity in both populations. The question with the highest positive predictive value (90.8% well-cohort and 84.6% BPD cohort) for both the groups was whether the child had been exposed to in-home smoking in the last 7 days. The question with the highest accuracy for both groups was the number of smokers at home (0 vs ≥ 1), with an accuracy of 72.4% for well children and 79.0% for the BPD cohort. Conclusions: There was a wide variability in the performance of specific questions. These data demonstrate that a “one-size-fits-all” approach to screening for secondhand tobacco smoke exposure may not be appropriate for all pediatric populations.

Original languageEnglish (US)
Pages (from-to)1-8
Number of pages8
JournalJournal of Exposure Science and Environmental Epidemiology
DOIs
StateAccepted/In press - Jul 16 2018

Fingerprint

Nicotine
Bronchopulmonary Dysplasia
Tobacco Smoke Pollution
Pediatrics
Tobacco
Smoke
Hair
Screening
Biomarkers
Population
Smoking
Research Personnel

Keywords

  • biomarkers
  • hair nicotine levels
  • secondhand smoke exposure

ASJC Scopus subject areas

  • Epidemiology
  • Toxicology
  • Pollution
  • Public Health, Environmental and Occupational Health

Cite this

Assessing pediatric tobacco exposure using parent report : comparison with hair nicotine. / Groner, Judith A.; Rule, Ana M; McGrath-Morrow, Sharon A; Collaco, Michael; Moss, Angela; Tanski, Susanne E.; McMillen, Robert; Whitmore, Regina M.; Klein, Jonathan D.; Winickoff, Jonathan P.; Wilson, Karen.

In: Journal of Exposure Science and Environmental Epidemiology, 16.07.2018, p. 1-8.

Research output: Contribution to journalArticle

Groner, Judith A. ; Rule, Ana M ; McGrath-Morrow, Sharon A ; Collaco, Michael ; Moss, Angela ; Tanski, Susanne E. ; McMillen, Robert ; Whitmore, Regina M. ; Klein, Jonathan D. ; Winickoff, Jonathan P. ; Wilson, Karen. / Assessing pediatric tobacco exposure using parent report : comparison with hair nicotine. In: Journal of Exposure Science and Environmental Epidemiology. 2018 ; pp. 1-8.
@article{4c08e7b0d2354223b43559a38e9f055c,
title = "Assessing pediatric tobacco exposure using parent report: comparison with hair nicotine",
abstract = "Introduction: The purpose of this study was to examine the relationships between screening questions for secondhand smoke (SHS) exposure and biomarker results using hair nicotine levels. Our ultimate goal was to develop sensitive and valid screening tools in pediatric clinical settings for SHS exposure. Methods: Investigators developed a core set of questions regarding exposure. Data from two separate ongoing studies of well children and those with bronchopulmonary dysplasia (BPD) were used to assess the concordance between responses and hair nicotine levels. Sensitivity, a positive predictive value, and accuracy were examined. Results: There was no single question with similar sensitivity in both populations. The question with the highest positive predictive value (90.8{\%} well-cohort and 84.6{\%} BPD cohort) for both the groups was whether the child had been exposed to in-home smoking in the last 7 days. The question with the highest accuracy for both groups was the number of smokers at home (0 vs ≥ 1), with an accuracy of 72.4{\%} for well children and 79.0{\%} for the BPD cohort. Conclusions: There was a wide variability in the performance of specific questions. These data demonstrate that a “one-size-fits-all” approach to screening for secondhand tobacco smoke exposure may not be appropriate for all pediatric populations.",
keywords = "biomarkers, hair nicotine levels, secondhand smoke exposure",
author = "Groner, {Judith A.} and Rule, {Ana M} and McGrath-Morrow, {Sharon A} and Michael Collaco and Angela Moss and Tanski, {Susanne E.} and Robert McMillen and Whitmore, {Regina M.} and Klein, {Jonathan D.} and Winickoff, {Jonathan P.} and Karen Wilson",
year = "2018",
month = "7",
day = "16",
doi = "10.1038/s41370-018-0051-z",
language = "English (US)",
pages = "1--8",
journal = "Journal of Exposure Science and Environmental Epidemiology",
issn = "1559-0631",
publisher = "Nature Publishing Group",

}

TY - JOUR

T1 - Assessing pediatric tobacco exposure using parent report

T2 - comparison with hair nicotine

AU - Groner, Judith A.

AU - Rule, Ana M

AU - McGrath-Morrow, Sharon A

AU - Collaco, Michael

AU - Moss, Angela

AU - Tanski, Susanne E.

AU - McMillen, Robert

AU - Whitmore, Regina M.

AU - Klein, Jonathan D.

AU - Winickoff, Jonathan P.

AU - Wilson, Karen

PY - 2018/7/16

Y1 - 2018/7/16

N2 - Introduction: The purpose of this study was to examine the relationships between screening questions for secondhand smoke (SHS) exposure and biomarker results using hair nicotine levels. Our ultimate goal was to develop sensitive and valid screening tools in pediatric clinical settings for SHS exposure. Methods: Investigators developed a core set of questions regarding exposure. Data from two separate ongoing studies of well children and those with bronchopulmonary dysplasia (BPD) were used to assess the concordance between responses and hair nicotine levels. Sensitivity, a positive predictive value, and accuracy were examined. Results: There was no single question with similar sensitivity in both populations. The question with the highest positive predictive value (90.8% well-cohort and 84.6% BPD cohort) for both the groups was whether the child had been exposed to in-home smoking in the last 7 days. The question with the highest accuracy for both groups was the number of smokers at home (0 vs ≥ 1), with an accuracy of 72.4% for well children and 79.0% for the BPD cohort. Conclusions: There was a wide variability in the performance of specific questions. These data demonstrate that a “one-size-fits-all” approach to screening for secondhand tobacco smoke exposure may not be appropriate for all pediatric populations.

AB - Introduction: The purpose of this study was to examine the relationships between screening questions for secondhand smoke (SHS) exposure and biomarker results using hair nicotine levels. Our ultimate goal was to develop sensitive and valid screening tools in pediatric clinical settings for SHS exposure. Methods: Investigators developed a core set of questions regarding exposure. Data from two separate ongoing studies of well children and those with bronchopulmonary dysplasia (BPD) were used to assess the concordance between responses and hair nicotine levels. Sensitivity, a positive predictive value, and accuracy were examined. Results: There was no single question with similar sensitivity in both populations. The question with the highest positive predictive value (90.8% well-cohort and 84.6% BPD cohort) for both the groups was whether the child had been exposed to in-home smoking in the last 7 days. The question with the highest accuracy for both groups was the number of smokers at home (0 vs ≥ 1), with an accuracy of 72.4% for well children and 79.0% for the BPD cohort. Conclusions: There was a wide variability in the performance of specific questions. These data demonstrate that a “one-size-fits-all” approach to screening for secondhand tobacco smoke exposure may not be appropriate for all pediatric populations.

KW - biomarkers

KW - hair nicotine levels

KW - secondhand smoke exposure

UR - http://www.scopus.com/inward/record.url?scp=85049946958&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85049946958&partnerID=8YFLogxK

U2 - 10.1038/s41370-018-0051-z

DO - 10.1038/s41370-018-0051-z

M3 - Article

C2 - 30013229

AN - SCOPUS:85049946958

SP - 1

EP - 8

JO - Journal of Exposure Science and Environmental Epidemiology

JF - Journal of Exposure Science and Environmental Epidemiology

SN - 1559-0631

ER -