TY - JOUR
T1 - Artifact-free coronary magnetic resonance angiography and coronary vessel wall imaging in the presence of a new, metallic, coronary magnetic resonance imaging stent
AU - Spuentrup, Elmar
AU - Ruebben, Alexander
AU - Mahnken, Andreas
AU - Stuber, Matthias
AU - Kölker, Christian
AU - Trung, Hieu Nguyen
AU - Günther, Rolf W.
AU - Buecker, Arno
N1 - Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2005/3/1
Y1 - 2005/3/1
N2 - Background - Coronary in-stent restenosis cannot be directly assessed by magnetic resonance angiography (MRA) because of the local signal void of currently used stainless steel stents. The aim of this study was to investigate the potential of a new, dedicated, coronary MR imaging (MRI) stent for artifact-free, coronary MRA and in-stent lumen and vessel wall visualization. Methods and Results - Fifteen prototype stents were deployed in coronary arteries of 15 healthy swine and investigated with a double-oblique, navigator-gated, free-breathing, T2-prepared, 3D cartesian gradient-echo sequence; a T2-prepared, 3D spiral gradient-echo sequence; and a T2-prepared, 3D steady-state, free-precession coronary MRA sequence. Furthermore, black-blood vessel wall imaging by a dual-inversion-recovery, turbo spin-echo sequence was performed. Artifacts of the stented vessel segment and signal intensities of the coronary vessel lumen inside and outside the stent were assessed. With all investigated sequences, the vessel lumen and wall could be visualized without artifacts, including the stented vessel segment. No signal intensity alterations inside the stent when compared with the vessel lumen outside the stent were found. Conclusions - The new, coronary MRI stent allows for completely artifact-free coronary MRA and vessel wall imaging.
AB - Background - Coronary in-stent restenosis cannot be directly assessed by magnetic resonance angiography (MRA) because of the local signal void of currently used stainless steel stents. The aim of this study was to investigate the potential of a new, dedicated, coronary MR imaging (MRI) stent for artifact-free, coronary MRA and in-stent lumen and vessel wall visualization. Methods and Results - Fifteen prototype stents were deployed in coronary arteries of 15 healthy swine and investigated with a double-oblique, navigator-gated, free-breathing, T2-prepared, 3D cartesian gradient-echo sequence; a T2-prepared, 3D spiral gradient-echo sequence; and a T2-prepared, 3D steady-state, free-precession coronary MRA sequence. Furthermore, black-blood vessel wall imaging by a dual-inversion-recovery, turbo spin-echo sequence was performed. Artifacts of the stented vessel segment and signal intensities of the coronary vessel lumen inside and outside the stent were assessed. With all investigated sequences, the vessel lumen and wall could be visualized without artifacts, including the stented vessel segment. No signal intensity alterations inside the stent when compared with the vessel lumen outside the stent were found. Conclusions - The new, coronary MRI stent allows for completely artifact-free coronary MRA and vessel wall imaging.
KW - Artifacts
KW - Coronary disease
KW - Magnetic resonance imaging
KW - Restenosis
KW - Stents
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U2 - 10.1161/01.CIR.0000156462.97532.8F
DO - 10.1161/01.CIR.0000156462.97532.8F
M3 - Article
C2 - 15723984
AN - SCOPUS:14844362253
SN - 0009-7322
VL - 111
SP - 1019
EP - 1026
JO - Circulation
JF - Circulation
IS - 8
ER -