Arthroscopic filling of talar osteochondral defects with stem cell-rich collagen paste

Stuart D. Miller; Lew C. Schon

doi:10.1097/BTF.0b013e31824f17d7

Arthroscopic filling of talar osteochondral defects with stem cell-rich collagen paste

Stuart D. Miller, Lew C. Schon

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

A novel technique of filling osteochondral defects in the talus is described using a paste of concentrated autologous bone marrow aspirate mixed with particulate collagen/glycosaminoglycan. After arthroscopic debridement and microfracture, the paste is applied under dry arthroscopic conditions with a fibrin glue covering. The paste can also be applied with open arthrotomy. The procedure offers the delivery of stem cells and growth factors to the damaged joint surface with minimal morbidity. Early anecdotal results are good, but longer study will be needed to discern an improvement over basic microfracture techniques.

Original language	English (US)
Pages (from-to)	135-139
Number of pages	5
Journal	Techniques in Foot and Ankle Surgery
Volume	11
Issue number	3
DOIs	https://doi.org/10.1097/BTF.0b013e31824f17d7
State	Published - Sep 2012
Externally published	Yes

Keywords

ankle
arthroscopy
bone marrow aspirate
osteochondra
talus

ASJC Scopus subject areas

Surgery
Orthopedics and Sports Medicine

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10.1097/BTF.0b013e31824f17d7

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abstract = "A novel technique of filling osteochondral defects in the talus is described using a paste of concentrated autologous bone marrow aspirate mixed with particulate collagen/glycosaminoglycan. After arthroscopic debridement and microfracture, the paste is applied under dry arthroscopic conditions with a fibrin glue covering. The paste can also be applied with open arthrotomy. The procedure offers the delivery of stem cells and growth factors to the damaged joint surface with minimal morbidity. Early anecdotal results are good, but longer study will be needed to discern an improvement over basic microfracture techniques.",

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AB - A novel technique of filling osteochondral defects in the talus is described using a paste of concentrated autologous bone marrow aspirate mixed with particulate collagen/glycosaminoglycan. After arthroscopic debridement and microfracture, the paste is applied under dry arthroscopic conditions with a fibrin glue covering. The paste can also be applied with open arthrotomy. The procedure offers the delivery of stem cells and growth factors to the damaged joint surface with minimal morbidity. Early anecdotal results are good, but longer study will be needed to discern an improvement over basic microfracture techniques.

KW - ankle

KW - arthroscopy

KW - bone marrow aspirate

KW - osteochondra

KW - talus

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Arthroscopic filling of talar osteochondral defects with stem cell-rich collagen paste

Abstract

Keywords

ASJC Scopus subject areas

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