Arterial Spin Labeling: a one-stop-shop for measurement of brain perfusion in the clinical settings.

Xavier Golay, Esben T. Petersen, Ivan Zimine, Tchoyoson C C Lim

Research output: Contribution to journalArticle

Abstract

Arterial Spin Labeling (ASL) has opened a unique window into the human brain function and perfusion physiology. Altogether fast and of intrinsic high spatial resolution, ASL is a technique very appealing not only for the diagnosis of vascular diseases, but also in basic neuroscience for the follow-up of small perfusion changes occurring during brain activation. However, due to limited signal-to-noise ratio and complex flow kinetics, ASL is one of the more challenging disciplines within magnetic resonance imaging. In this paper, the theoretical background and main implementations of ASL are revisited. In particular, the different uses of ASL, the pitfalls and possibilities are described and illustrated using clinical cases.

Original languageEnglish (US)
Pages (from-to)4320-4323
Number of pages4
JournalConference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference
StatePublished - 2007
Externally publishedYes

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Labeling
Brain
Perfusion
Signal-To-Noise Ratio
Neurosciences
Vascular Diseases
Magnetic Resonance Imaging
Physiology
Magnetic resonance
Signal to noise ratio
Chemical activation
Imaging techniques
Kinetics

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Biomedical Engineering
  • Health Informatics

Cite this

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