Arterial pulse wave velocity as a marker of poor cognitive function in an elderly community-dwelling population

Yoshinori Fujiwara, Paulo H M Chaves, Ryutaro Takahashi, Hidenori Amano, Hiroto Yoshida, Shu Kumagai, Koji Fujita, Dou Gui Wang, Shoji Shinkai

Research output: Contribution to journalArticle

Abstract

Background. Knowledge about potentially modifiable risk factors for cognitive decline is limited at this time. The aim of this study was to determine the cross-sectional relationship between a low level of cognitive function and brachial-ankle pulse wave velocity (baPWV) in a community-dwelling elderly population. Methods. The study population included 352 community-dwelling Japanese persons ages 70 years and older who participated in a comprehensive health examination in April 2003. None had any history of cardiovascular disease. In addition to conventional medical examinations such as blood pressure and routine blood analyses, cognitive function was tested using the Mini-Mental State Examination (MMSE), and baPWV was determined using a recently developed noninvasive and automatic arterial waveform analyzer (AT-Form). This measure, with well-established validity and reproducibility, reflects both central and peripheral arterial flow. A multivariate logistic regression model tested the possible association between poor cognitive function (an MMSE score

Original languageEnglish (US)
Pages (from-to)607-612
Number of pages6
JournalJournals of Gerontology - Series A Biological Sciences and Medical Sciences
Volume60
Issue number5
StatePublished - May 2005

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Independent Living
Pulse Wave Analysis
Cognition
Ankle
Arm
Logistic Models
Population
Cardiovascular Diseases
Blood Pressure
Health

ASJC Scopus subject areas

  • Aging

Cite this

Fujiwara, Y., Chaves, P. H. M., Takahashi, R., Amano, H., Yoshida, H., Kumagai, S., ... Shinkai, S. (2005). Arterial pulse wave velocity as a marker of poor cognitive function in an elderly community-dwelling population. Journals of Gerontology - Series A Biological Sciences and Medical Sciences, 60(5), 607-612.

Arterial pulse wave velocity as a marker of poor cognitive function in an elderly community-dwelling population. / Fujiwara, Yoshinori; Chaves, Paulo H M; Takahashi, Ryutaro; Amano, Hidenori; Yoshida, Hiroto; Kumagai, Shu; Fujita, Koji; Wang, Dou Gui; Shinkai, Shoji.

In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences, Vol. 60, No. 5, 05.2005, p. 607-612.

Research output: Contribution to journalArticle

Fujiwara, Y, Chaves, PHM, Takahashi, R, Amano, H, Yoshida, H, Kumagai, S, Fujita, K, Wang, DG & Shinkai, S 2005, 'Arterial pulse wave velocity as a marker of poor cognitive function in an elderly community-dwelling population', Journals of Gerontology - Series A Biological Sciences and Medical Sciences, vol. 60, no. 5, pp. 607-612.
Fujiwara, Yoshinori ; Chaves, Paulo H M ; Takahashi, Ryutaro ; Amano, Hidenori ; Yoshida, Hiroto ; Kumagai, Shu ; Fujita, Koji ; Wang, Dou Gui ; Shinkai, Shoji. / Arterial pulse wave velocity as a marker of poor cognitive function in an elderly community-dwelling population. In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 2005 ; Vol. 60, No. 5. pp. 607-612.
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