Arterial blood gas derived variables as estimates of intrapulmonary shunt in critically ill children

J. M. Dean, R. C. Wetzel, M. C. Rogers

Research output: Contribution to journalArticlepeer-review

Abstract

Oxygen transport data, prospectively collected from 52 critically ill children, were analyzed to determine whether any derived variable accurately estimated intrapulmonary shunt (Q̇sp/Q̇t). Arterial hemoglobin saturation was more closely correlated with Q̇sp/Q̇t than was PaO2, alveolar-arterial oxygen gradient, arterial mixed venous oxygen difference (C[a-v̄]o2), arterial/alveolar oxygen ratio, and the ratio of PaO2 to inspired oxygen (FIO2) (r = 0.8, P < .0001). When C(a-v̄)o2 was normal, hemoglobin saturation became a very accurate (r = 0.96) assessment of Q̇sp/Q̇t. We conclude that various blood gas derived variables do not accurately reflect Q̇sp/Q̇t in critically ill children. In these patients, a pulmonary artery catheter is needed to accurately assess intrapulmonary shunt.

Original languageEnglish (US)
Pages (from-to)1029-1033
Number of pages5
JournalCritical care medicine
Volume13
Issue number12
DOIs
StatePublished - Jan 1 1985

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

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