Arrhythmogenic right ventricular dysplasia/ cardiomyopathy and cardiac sarcoidosis distinguishing features when the diagnosis is unclear

Binu Philips, Srinivasa Madhavan, Cynthia Anne James, Anneline S J M Te Riele, Brittney Murray, Crystal Tichnell, Aditya Bhonsale, Saman Nazarian, Daniel P. Judge, Hugh Calkins, Harikrishna Tandri, Alan Cheng

Research output: Contribution to journalArticle

Abstract

Background-Cardiac sarcoidosis (CS) may show overlap in the clinical presentation with arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C). We sought to investigate patients with CS who were misdiagnosed with ARVD/C and identify clinical features to distinguish these 2 groups. Methods and Results-Among patients enrolled in the Johns Hopkins ARVD/C registry, 15 patients with definite 2010 diagnostic criteria for ARVD/C were subsequently diagnosed with CS. Forty-two pathogenic desmosomal mutation carriers with definite ARVD/C based on the 2010 diagnostic criteria served as a control group. Patients with CS were older at the age of symptom onset, more likely to have comorbidities, and develop heart failure symptoms over time (P

Original languageEnglish (US)
Pages (from-to)230-236
Number of pages7
JournalCirculation: Arrhythmia and Electrophysiology
Volume7
Issue number2
DOIs
StatePublished - 2014

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Arrhythmogenic Right Ventricular Dysplasia
Sarcoidosis
Diagnostic Errors
Age of Onset
Registries
Comorbidity
Heart Failure
Control Groups
Mutation

Keywords

  • Arrhythmogenic right ventricular dysplasia
  • Diagnosis
  • Sarcoidosis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

Cite this

Arrhythmogenic right ventricular dysplasia/ cardiomyopathy and cardiac sarcoidosis distinguishing features when the diagnosis is unclear. / Philips, Binu; Madhavan, Srinivasa; James, Cynthia Anne; Riele, Anneline S J M Te; Murray, Brittney; Tichnell, Crystal; Bhonsale, Aditya; Nazarian, Saman; Judge, Daniel P.; Calkins, Hugh; Tandri, Harikrishna; Cheng, Alan.

In: Circulation: Arrhythmia and Electrophysiology, Vol. 7, No. 2, 2014, p. 230-236.

Research output: Contribution to journalArticle

Philips, Binu ; Madhavan, Srinivasa ; James, Cynthia Anne ; Riele, Anneline S J M Te ; Murray, Brittney ; Tichnell, Crystal ; Bhonsale, Aditya ; Nazarian, Saman ; Judge, Daniel P. ; Calkins, Hugh ; Tandri, Harikrishna ; Cheng, Alan. / Arrhythmogenic right ventricular dysplasia/ cardiomyopathy and cardiac sarcoidosis distinguishing features when the diagnosis is unclear. In: Circulation: Arrhythmia and Electrophysiology. 2014 ; Vol. 7, No. 2. pp. 230-236.
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AU - Murray, Brittney

AU - Tichnell, Crystal

AU - Bhonsale, Aditya

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AU - Cheng, Alan

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