Abstract
Pancreatic cancer, the fourth leading cause of cancer death in the United States, is frequently associated with the amplification and deletion of specific oncogenes and tumor-suppressor genes (TSGs), respectively. To identify such novel alterations and to discover the underlying genes, we performed comparative genomic hybridization on a set of 22 human pancreatic cancer cell lines, using cDNA microarrays measuring ∼26,000 human genes (thereby providing an average mapping resolution of
Original language | English (US) |
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Pages (from-to) | 556-562 |
Number of pages | 7 |
Journal | Neoplasia |
Volume | 7 |
Issue number | 6 |
DOIs | |
State | Published - Jun 2005 |
Keywords
- Array CGH
- Comparative genomic hybridization
- DNA amplification
- Expression profiling
- Pancreatic cancer
ASJC Scopus subject areas
- Cancer Research