Are constitutional delay of growth and familial short stature different conditions?

R. Lanes, P. A. Lee, L. P. Plotnick, A. A. Kowarski, C. J. Migeon

Research output: Contribution to journalArticle

Abstract

Children between 2 and 4 standard deviations below the mean height for age with no specific cause to account for their short stature are usually considered to represent either constitutional delay of growth (CDG) or familial short stature (FSS). This study was undertaken to determine whether 167 patients who were referred to the clinic for short stature could be divided into two distinct populations that fit the criteria of CDG and FSS. When the patients were artificially divided into 2 subgroups based on skeletal age greater or less than 2 standard deviations below the mean, no significant difference in growth rates or midparental heights could be found between them. Height ages were significantly more delayed in the group with greater skeletal age delay. Midparental height of the total population of short children was less than the mean midparental height of normal American children. It was concluded that these patients did not distribute into these two clear-cut entities. Whether they represented one continuum or two largely overlapping populations could not be decided on the basis of data.

Original languageEnglish (US)
Pages (from-to)31-33
Number of pages3
JournalClinical Pediatrics
Volume19
Issue number1
StatePublished - 1980

    Fingerprint

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Lanes, R., Lee, P. A., Plotnick, L. P., Kowarski, A. A., & Migeon, C. J. (1980). Are constitutional delay of growth and familial short stature different conditions? Clinical Pediatrics, 19(1), 31-33.