Aqueous humor lactic acid dehydrogenase in retinoblastoma

M. Swartz, R. W. Herbst, Morton F Goldberg

Research output: Contribution to journalArticle

Abstract

Thirty three patients underwent analysis for aqueous humor and serum lactic acid dehydrogenase (LDH) concentrations. By comparison of the ratios of aqueous humor LDH to serum LDH, the assayed patients fell into 3 catagories. There were 6 retinoblastomas for which ratios were calculated; all ratios in these cases were greater than 1.50. One case of active nematode endophthalmitis had a ratio of 1.03, presumably secondary to disruption of the blood vitreous barrier. The remainder of the cases (including other cases of nematode endophthalmitis, traumatic intravitreous and intraretinal hemorrhage, traumatic retinal detachment with rubeosis iridis, persistent hyperplastic primary vitreous, choroidal hemangioma, retrolental fibroplasia, pediatric cataracts, malignant melanomas, and senile cataracts) had ratios below 0.60. This separation of patients into retinoblastoma and nonretinoblastoma populations was done by a routine clinical laboratory assay.

Original languageEnglish (US)
Pages (from-to)612-617
Number of pages6
JournalAmerican Journal of Ophthalmology
Volume78
Issue number4
StatePublished - 1974
Externally publishedYes

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Retinoblastoma
Aqueous Humor
Lactic Acid
Oxidoreductases
Endophthalmitis
Cataract
Persistent Hyperplastic Primary Vitreous
Retinopathy of Prematurity
Retinal Detachment
Hemangioma
Serum
Melanoma
Pediatrics
Hemorrhage
Population

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Aqueous humor lactic acid dehydrogenase in retinoblastoma. / Swartz, M.; Herbst, R. W.; Goldberg, Morton F.

In: American Journal of Ophthalmology, Vol. 78, No. 4, 1974, p. 612-617.

Research output: Contribution to journalArticle

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