Abstract
Thirty three patients underwent analysis for aqueous humor and serum lactic acid dehydrogenase (LDH) concentrations. By comparison of the ratios of aqueous humor LDH to serum LDH, the assayed patients fell into 3 catagories. There were 6 retinoblastomas for which ratios were calculated; all ratios in these cases were greater than 1.50. One case of active nematode endophthalmitis had a ratio of 1.03, presumably secondary to disruption of the blood vitreous barrier. The remainder of the cases (including other cases of nematode endophthalmitis, traumatic intravitreous and intraretinal hemorrhage, traumatic retinal detachment with rubeosis iridis, persistent hyperplastic primary vitreous, choroidal hemangioma, retrolental fibroplasia, pediatric cataracts, malignant melanomas, and senile cataracts) had ratios below 0.60. This separation of patients into retinoblastoma and nonretinoblastoma populations was done by a routine clinical laboratory assay.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 612-617 |
| Number of pages | 6 |
| Journal | American Journal of Ophthalmology |
| Volume | 78 |
| Issue number | 4 |
| State | Published - 1974 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Ophthalmology
Cite this
Aqueous humor lactic acid dehydrogenase in retinoblastoma. / Swartz, M.; Herbst, R. W.; Goldberg, Morton F.
In: American Journal of Ophthalmology, Vol. 78, No. 4, 1974, p. 612-617.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Aqueous humor lactic acid dehydrogenase in retinoblastoma
AU - Swartz, M.
AU - Herbst, R. W.
AU - Goldberg, Morton F
PY - 1974
Y1 - 1974
N2 - Thirty three patients underwent analysis for aqueous humor and serum lactic acid dehydrogenase (LDH) concentrations. By comparison of the ratios of aqueous humor LDH to serum LDH, the assayed patients fell into 3 catagories. There were 6 retinoblastomas for which ratios were calculated; all ratios in these cases were greater than 1.50. One case of active nematode endophthalmitis had a ratio of 1.03, presumably secondary to disruption of the blood vitreous barrier. The remainder of the cases (including other cases of nematode endophthalmitis, traumatic intravitreous and intraretinal hemorrhage, traumatic retinal detachment with rubeosis iridis, persistent hyperplastic primary vitreous, choroidal hemangioma, retrolental fibroplasia, pediatric cataracts, malignant melanomas, and senile cataracts) had ratios below 0.60. This separation of patients into retinoblastoma and nonretinoblastoma populations was done by a routine clinical laboratory assay.
AB - Thirty three patients underwent analysis for aqueous humor and serum lactic acid dehydrogenase (LDH) concentrations. By comparison of the ratios of aqueous humor LDH to serum LDH, the assayed patients fell into 3 catagories. There were 6 retinoblastomas for which ratios were calculated; all ratios in these cases were greater than 1.50. One case of active nematode endophthalmitis had a ratio of 1.03, presumably secondary to disruption of the blood vitreous barrier. The remainder of the cases (including other cases of nematode endophthalmitis, traumatic intravitreous and intraretinal hemorrhage, traumatic retinal detachment with rubeosis iridis, persistent hyperplastic primary vitreous, choroidal hemangioma, retrolental fibroplasia, pediatric cataracts, malignant melanomas, and senile cataracts) had ratios below 0.60. This separation of patients into retinoblastoma and nonretinoblastoma populations was done by a routine clinical laboratory assay.
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UR - http://www.scopus.com/inward/citedby.url?scp=0016277649&partnerID=8YFLogxK
M3 - Article
VL - 78
SP - 612
EP - 617
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
SN - 0002-9394
IS - 4
ER -