Aquaporin water channels

unanswered questions and unresolved controversies

Peter C Agre, Dennis Brown, Søren Nielsen

Research output: Contribution to journalArticle

Abstract

The long-standing biophysical question of how water crosses plasma membranes has been answered by the recent discovery of the aquaporins. Identification of this large family of membrane water-transport proteins has generated new questions about the physiological functions, tissue distributions, and regulatory mechanisms of individual aquaporins. The fast pace of developments in this field has also resulted in major discrepancies in published reports which warrant resolution.

Original languageEnglish (US)
Pages (from-to)472-483
Number of pages12
JournalCurrent Opinion in Cell Biology
Volume7
Issue number4
DOIs
StatePublished - 1995

Fingerprint

Aquaporins
Membrane Transport Proteins
Water
Tissue Distribution
Cell Membrane

ASJC Scopus subject areas

  • Cell Biology

Cite this

Aquaporin water channels : unanswered questions and unresolved controversies. / Agre, Peter C; Brown, Dennis; Nielsen, Søren.

In: Current Opinion in Cell Biology, Vol. 7, No. 4, 1995, p. 472-483.

Research output: Contribution to journalArticle

Agre, Peter C ; Brown, Dennis ; Nielsen, Søren. / Aquaporin water channels : unanswered questions and unresolved controversies. In: Current Opinion in Cell Biology. 1995 ; Vol. 7, No. 4. pp. 472-483.
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