TY - JOUR
T1 - Appropriate BMI cut-off values for identification of metabolic risk factors
T2 - Third national surveillance of risk factors of non-communicable diseases in Iran (SuRFNCD-2007)
AU - Zandieh, Ali
AU - Esteghamati, Alireza
AU - Morteza, Afsaneh
AU - Noshad, Sina
AU - Khalilzadeh, Omid
AU - Gouya, Mohammad Mehdi
AU - Nakhjavani, Manouchehr
N1 - Copyright:
Copyright 2013 Elsevier B.V., All rights reserved.
PY - 2012/11
Y1 - 2012/11
N2 - Aim: To determine the appropriate threshold of body mass index (BMI) associated with increased risk of cardiovascular diseases in a large representative sample of an Iranian population. Subjects and methods: Data of third national surveillance of risk factors of non-communicable diseases (SuRFNCD-2007) were used in this study. Sensitivity, specificity, and shortest distance on the receiver-operating characteristic (ROC) curves were used to determine gender-specific optimal cut-offs of BMI for cardiometabolic risk factors including elevated blood pressure, low high-density lipoprotein cholesterol, high triglycerides, high fasting plasma glucose and for ≥ 2 of the aforementioned risk factors. Results: There was a continuous increase in the prevalence of cardiometabolic risk factors with increasing BMI (p < 0.001). At the BMI of 2529 kg/m2 men were at higher risk of cardiovascular diseases compared to women (p < 0.001). The appropriate BMI cut-offs ranged from 24.626.1 kg/m2 for men and from 26.928.8 kg/m2 for women. The optimal BMI cut-offs for identifying any two or more of those risk factors were 25.2 and 27.3 kg/m2 in men and women, respectively. Conclusion: In men the appropriate BMI cut-offs are ∼25 kg/m2, while in women higher BMI values are associated with risk of cardiovascular diseases.
AB - Aim: To determine the appropriate threshold of body mass index (BMI) associated with increased risk of cardiovascular diseases in a large representative sample of an Iranian population. Subjects and methods: Data of third national surveillance of risk factors of non-communicable diseases (SuRFNCD-2007) were used in this study. Sensitivity, specificity, and shortest distance on the receiver-operating characteristic (ROC) curves were used to determine gender-specific optimal cut-offs of BMI for cardiometabolic risk factors including elevated blood pressure, low high-density lipoprotein cholesterol, high triglycerides, high fasting plasma glucose and for ≥ 2 of the aforementioned risk factors. Results: There was a continuous increase in the prevalence of cardiometabolic risk factors with increasing BMI (p < 0.001). At the BMI of 2529 kg/m2 men were at higher risk of cardiovascular diseases compared to women (p < 0.001). The appropriate BMI cut-offs ranged from 24.626.1 kg/m2 for men and from 26.928.8 kg/m2 for women. The optimal BMI cut-offs for identifying any two or more of those risk factors were 25.2 and 27.3 kg/m2 in men and women, respectively. Conclusion: In men the appropriate BMI cut-offs are ∼25 kg/m2, while in women higher BMI values are associated with risk of cardiovascular diseases.
KW - BMI
KW - Metabolic risk factors
KW - Obesity
KW - Receiver-operating characteristic curve
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U2 - 10.3109/03014460.2012.716860
DO - 10.3109/03014460.2012.716860
M3 - Article
C2 - 22946480
AN - SCOPUS:84868090404
SN - 0301-4460
VL - 39
SP - 484
EP - 489
JO - Annals of Human Biology
JF - Annals of Human Biology
IS - 6
ER -