Approaches to Morbidly Obese Women with Gynecologic Cancer

Karime K. Machado, Amanda N. Fader

Research output: Contribution to journalReview articlepeer-review


Modifiable lifestyle factors, such as obesity, contribute significantly to cancer and preventable death worldwide. This review appraises recent evidence on the relationship of obesity with endometrial cancer, ovarian cancer, and other gynecologic malignancies as well as new evidence for the best surgical and medical practices in morbidly obese female cancer patients, including utilization of minimally invasive surgery, cytoreductive surgery, appropriate chemotherapy dosing, and optimizing radiation therapy in this population. For gynecologic cancer survivors, physical activity and weight loss are associated with improved health and quality of life. Interventional trials show promise in increasing physical activity and weight loss. Women’s cancer care providers should integrate counseling about obesity in the management of survivors of gynecologic cancers.

Original languageEnglish (US)
Pages (from-to)286-295
Number of pages10
JournalCurrent Obstetrics and Gynecology Reports
Issue number4
StatePublished - Dec 1 2016


  • Gynecologic cancer
  • Obesity
  • Quality of life
  • Survivorship
  • Weight loss

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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