Application of the 4D XCAT Phantoms in Biomedical Imaging and Beyond

W. Paul Segars, Benjamin Tsui, Jing Cai, Fang Fang Yin, George S.K. Fung, Ehsan Samei

Research output: Contribution to journalArticle

Abstract

The four dimensional (4D) eXtended CArdiac-Torso (XCAT) series of phantoms was developed to provide accurate computerized models of the human anatomy and physiology. The XCAT series encompasses a vast population of phantoms of varying ages from newborn to adult, each including parameterized models for the cardiac and respiratory motions. With great flexibility in the XCAT’s design, any number of body sizes, different anatomies, cardiac or respiratory motions or patterns, patient positions and orientations, and spatial resolutions can be simulated. As such, the XCAT phantoms are gaining a wide use in biomedical imaging research. There they can provide a virtual patient base from which to quantitatively evaluate and improve imaging instrumentation, data acquisition, techniques and image reconstruction and processing methods which can lead to improved image quality and more accurate clinical diagnoses. The phantoms have also found great use in radiation dosimetry, radiation therapy, medical device design, and even the security and defense industry. This review paper highlights some specific areas in which the XCAT phantoms have found use within biomedical imaging and other fields. From these examples, we illustrate the increasingly important role that computerized phantoms and computer simulation are playing in the research community.

Original languageEnglish (US)
JournalIEEE Transactions on Medical Imaging
DOIs
StateAccepted/In press - Aug 10 2017

Keywords

  • and SPECT
  • Biological system modeling
  • Biomedical imaging phantoms
  • Computational modeling
  • Computed tomography
  • CT
  • dosimetry
  • image analysis
  • image reconstruction
  • Imaging phantoms
  • medical diagnostic imaging
  • medical simulation
  • PET
  • Phantoms

ASJC Scopus subject areas

  • Software
  • Radiological and Ultrasound Technology
  • Computer Science Applications
  • Electrical and Electronic Engineering

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