Application of signature-tagged mutagenesis for identification of escherichia coli K1 genes that contribute to invasion of human brain microvascular endothelial cells

Agriculture & Biology

• endothelial cells 100%
• mutagenesis 93%
• brain 68%
• blood-brain barrier 64%
• meningitis 63%
• Escherichia coli 62%
• mutants 57%
• genes 33%
• pathogenesis 29%
• neonates 27%
• morbidity 17%
• transposons 14%
• animal models 14%
• loci 9%

Medicine & Life Sciences

• Mutagenesis 96%
• Endothelial Cells 72%
• Blood-Brain Barrier 70%
• Escherichia coli 68%
• Brain 47%
• Escherichia coli Meningitis 41%
• Genes 39%
• Bacterial Meningitides 30%
• Meningitis 24%
• Theoretical Models 19%
• Morbidity 14%
• Mortality 12%