Application of Human Leukocyte Antigen-G Expression in the Diagnosis of Human Cancer

Research output: Contribution to journalArticlepeer-review


It has been well known that human leukocyte antigen (HLA)-G molecules are present in a variety of human neoplastic diseases, and the molecule may contribute to the escape of tumor cells from immune surveillance. Besides the studies that aim at elucidating the roles of HLA-G in immune regulation, the researches that focus on potential applications of HLA-G expression in cancer diagnosis represent another perspective in HLA-G research. This review summarizes those recent translational studies of HLA-G expression in the diagnosis of human cancer. Specifically, the promises and challenges for applying HLA-G expression to detect cancer in body fluids, to diagnose different types of human cancer and to predict clinical outcome in cancer patients will be briefly reviewed.

Original languageEnglish (US)
Pages (from-to)272-276
Number of pages5
JournalHuman Immunology
Issue number4
StatePublished - Apr 2007


  • detection
  • diagnosis
  • human cancer
  • prognosis

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology


Dive into the research topics of 'Application of Human Leukocyte Antigen-G Expression in the Diagnosis of Human Cancer'. Together they form a unique fingerprint.

Cite this