Application of Chimera grid to modelling cell motion and aggregation in a narrow tube

B. Chung, P. C. Johnson, Aleksander S Popel

Research output: Contribution to journalArticle

Abstract

A computational scheme using the Chimera grid method is presented for simulation of three-dimensional motion and aggregation of two red blood cells (RBCs) in a narrow tube. The cells are modelled as rigid ellipsoidal particles; the computational scheme is applicable to deformable fluid-filled particles. Attractive energy between two RBCs is modelled by a depletion interaction theory and used for simulating aggregation of two cells. Through the simulation, we show that the Chimera grid method is applicable to the simulation of three-dimensional motion and aggregation of multiple RBCs in a microvessel and microvascular network.

Original languageEnglish (US)
Pages (from-to)105-128
Number of pages24
JournalINT. J. NUMER. METHODS FLUIDS
Volume53
Issue number1
DOIs
StatePublished - Jan 10 2007

Fingerprint

Red Blood Cells
erythrocytes
three dimensional motion
Aggregation
Tube
Blood
Agglomeration
grids
tubes
Grid
Motion
Cell
cells
Modeling
Three-dimensional
Simulation
simulation
Depletion
depletion
Cells

Keywords

  • Chimera grid
  • Depletion interaction energy
  • RBC aggregation
  • Red blood cell

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Safety, Risk, Reliability and Quality
  • Applied Mathematics
  • Computational Theory and Mathematics
  • Computer Science Applications
  • Computational Mechanics
  • Mechanics of Materials

Cite this

Application of Chimera grid to modelling cell motion and aggregation in a narrow tube. / Chung, B.; Johnson, P. C.; Popel, Aleksander S.

In: INT. J. NUMER. METHODS FLUIDS, Vol. 53, No. 1, 10.01.2007, p. 105-128.

Research output: Contribution to journalArticle

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