A 15-year-old phenotypic female with a Y/autosome translocation is reported. This patient had a 45,X,-16,+t(16 Yp-) 46,XYq-,-16,+t(16 Yp-) chromosome complement in a lymphocyte culture. Her left gonad showed dysgerminoma and a Sertoli-cell tumor. The right gonad showed gonadoblastoma in a streak and a poorly developed ovary. It was concluded that the pubertal events in this patient came from the estrogens secreted from a Sertoli-cell tumor rather than the function of poorly developed ovary.
ASJC Scopus subject areas
- Obstetrics and Gynecology