Apparent pseudopuberty in a phenotypic female with a gonadal tumor and an autosome/Y chromosome translocation

I. James Park, Richard H. Heller, Howard W. Jones, J. Donald Woodruff

Research output: Contribution to journalArticlepeer-review

Abstract

A 15-year-old phenotypic female with a Y/autosome translocation is reported. This patient had a 45,X,-16,+t(16 Yp-) 46,XYq-,-16,+t(16 Yp-) chromosome complement in a lymphocyte culture. Her left gonad showed dysgerminoma and a Sertoli-cell tumor. The right gonad showed gonadoblastoma in a streak and a poorly developed ovary. It was concluded that the pubertal events in this patient came from the estrogens secreted from a Sertoli-cell tumor rather than the function of poorly developed ovary.

Original languageEnglish (US)
Pages (from-to)661-668
Number of pages8
JournalAmerican journal of obstetrics and gynecology
Volume119
Issue number5
DOIs
StatePublished - Jul 1 1974

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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