Apoptosis - Molecular mechanisms and biomedical implications

David McConkey, Boris Zhivotovsky, Sten Orrenius

Research output: Contribution to journalArticle

Abstract

Apoptosis is a distinct form of cell death of importance in tissue development and homeostasis and in several diseases. This review summarizes current knowledge about the regulation and molecular mechanisms of apoptosis and discusses the potential role of disregulated apoptosis in several major diseases. Finally, we speculate that modulation of apoptosis may be a target in future drug therapy.

Original languageEnglish (US)
Pages (from-to)1-110
Number of pages110
JournalMolecular Aspects of Medicine
Volume17
Issue number1
DOIs
StatePublished - Feb 1996
Externally publishedYes

Fingerprint

Apoptosis
Drug therapy
Cell death
Homeostasis
Cell Death
Modulation
Tissue
Drug Therapy

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Molecular Medicine

Cite this

Apoptosis - Molecular mechanisms and biomedical implications. / McConkey, David; Zhivotovsky, Boris; Orrenius, Sten.

In: Molecular Aspects of Medicine, Vol. 17, No. 1, 02.1996, p. 1-110.

Research output: Contribution to journalArticle

McConkey, David ; Zhivotovsky, Boris ; Orrenius, Sten. / Apoptosis - Molecular mechanisms and biomedical implications. In: Molecular Aspects of Medicine. 1996 ; Vol. 17, No. 1. pp. 1-110.
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