Apoptosis - Molecular mechanisms and biomedical implications

David J. McConkey; Boris Zhivotovsky; Sten Orrenius

doi:10.1016/0098-2997(95)00006-2

Apoptosis - Molecular mechanisms and biomedical implications

David J. McConkey, Boris Zhivotovsky, Sten Orrenius

Research output: Contribution to journal › Review article › peer-review

107 Scopus citations

Abstract

Apoptosis is a distinct form of cell death of importance in tissue development and homeostasis and in several diseases. This review summarizes current knowledge about the regulation and molecular mechanisms of apoptosis and discusses the potential role of disregulated apoptosis in several major diseases. Finally, we speculate that modulation of apoptosis may be a target in future drug therapy.

Original language	English (US)
Pages (from-to)	1-3
Number of pages	3
Journal	Molecular Aspects of Medicine
Volume	17
Issue number	1
DOIs	https://doi.org/10.1016/0098-2997(95)00006-2
State	Published - Feb 1996
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Molecular Medicine
Molecular Biology
Clinical Biochemistry

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10.1016/0098-2997(95)00006-2

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title = "Apoptosis - Molecular mechanisms and biomedical implications",

abstract = "Apoptosis is a distinct form of cell death of importance in tissue development and homeostasis and in several diseases. This review summarizes current knowledge about the regulation and molecular mechanisms of apoptosis and discusses the potential role of disregulated apoptosis in several major diseases. Finally, we speculate that modulation of apoptosis may be a target in future drug therapy.",

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AB - Apoptosis is a distinct form of cell death of importance in tissue development and homeostasis and in several diseases. This review summarizes current knowledge about the regulation and molecular mechanisms of apoptosis and discusses the potential role of disregulated apoptosis in several major diseases. Finally, we speculate that modulation of apoptosis may be a target in future drug therapy.

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Apoptosis - Molecular mechanisms and biomedical implications

Abstract

ASJC Scopus subject areas

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