Apoptosis - Molecular mechanisms and biomedical implications

David J. McConkey, Boris Zhivotovsky, Sten Orrenius

Research output: Contribution to journalReview articlepeer-review


Apoptosis is a distinct form of cell death of importance in tissue development and homeostasis and in several diseases. This review summarizes current knowledge about the regulation and molecular mechanisms of apoptosis and discusses the potential role of disregulated apoptosis in several major diseases. Finally, we speculate that modulation of apoptosis may be a target in future drug therapy.

Original languageEnglish (US)
Pages (from-to)1-3
Number of pages3
JournalMolecular Aspects of Medicine
Issue number1
StatePublished - Feb 1996
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Clinical Biochemistry


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