APOL1 risk variants and death among African American hemodialysis patients: survival of the fittest?

Teresa Chen, Michelle M. Estrella

Research output: Contribution to journalComment/debate

Abstract

Recent studies have focused on associations of the APOL1 risk variants with outcomes beyond kidney disease, including cardiovascular disease and mortality. Ma and colleagues now expand on this growing but contradicting body of work. Their analysis of a prevalent cohort of African American hemodialysis patients shows that the risk variants are associated with a survival benefit among nondiabetics. Whether this simply reflects a healthier status at hemodialysis initiation among those carrying 2 risk variants or whether these variants truly confer a survival advantage is unclear.

Original languageEnglish (US)
Pages (from-to)249-252
Number of pages4
JournalKidney International
Volume90
Issue number2
DOIs
StatePublished - Aug 1 2016

ASJC Scopus subject areas

  • Medicine(all)
  • Nephrology

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