APOL1 Risk Alleles, Cardiac Markers, and Risk of ESKD in African Americans: The Atherosclerosis Risk in Communities Study

TY - JOUR

T1 - APOL1 Risk Alleles, Cardiac Markers, and Risk of ESKD in African Americans

T2 - The Atherosclerosis Risk in Communities Study

AU - Surapaneni, Aditya L.

AU - Ballew, Shoshana H.

AU - Coresh, Josef

AU - Ballantyne, Christie M.

AU - Selvin, Elizabeth

AU - Matsushita, Kunihiro

AU - Grams, Morgan E.

N1 - Funding Information: Dr Ballantyne has received grant/research support from Abbott and Roche, has been a consultant for Abbott and Roche, and is named in a provisional patent (patent no. 61721475) entitled “Biomarkers to Improve Prediction of Heart Failure Risk” filed by Baylor College of Medicine and Roche. Dr Matsushita received research funding and personal fee from Kyowa Kirin, personal fee from Akebia, and nonfinancial support from Roche Diagnostics outside of the work. Dr Grams received travel support from DCI. Funding Information: Aditya L. Surapaneni, PhD, Shoshana H. Ballew, PhD, Josef Coresh, MD, PhD, Christie M. Ballantyne, MD, Elizabeth Selvin, PhD, Kunihiro Matsushita, MD, PhD, and Morgan E. Grams, MD, PhD. Research idea and study design: AS, MEG; data acquisition: JC, CB, ES; data analysis/interpretation: AS, SHB, JC, ES, KM, MEG; statistical analysis: ALS; supervision or mentorship: MEG. Each author contributed important intellectual content during manuscript drafting or revision and accepts accountability for the overall work by ensuring that questions pertaining to the accuracy or integrity of any portion of the work are appropriately investigated and resolved. The ARIC Study has been funded in whole or in part with federal funds from the National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), Department of Health and Human Services, under contract nos. HHSN268201700001I, HHSN268201700002I, HHSN268201700003I, HHSN268201700005I, HHSN268201700004I; R01HL087641, R01HL086694; National Human Genome Research Institute contract U01HG004402; and NIH contract HHSN268200625226C. Funding for laboratory testing and biospecimen collection at ARIC Study visit 6 was supported by grant R01DK089174 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the NIH. Genotyping services were provided by the Johns Hopkins University under federal contract number N01-HV-48195 from the NHLBI and the Center for Inherited Disease Research (CIDR). CIDR is fully funded through a federal contract from the NIH to the Johns Hopkins University (contract no. N01-HG-65403). Drs Surapaneni, Coresh, and Grams also receive funding from NIDDK R01 DK108803. The funders of this study had no role in the study design; collection, analyses, and interpretation of data; writing of the report; or decision to submit the report for publication. Dr Ballantyne has received grant/research support from Abbott and Roche, has been a consultant for Abbott and Roche, and is named in a provisional patent (patent no. 61721475) entitled “Biomarkers to Improve Prediction of Heart Failure Risk” filed by Baylor College of Medicine and Roche. Dr Matsushita received research funding and personal fee from Kyowa Kirin, personal fee from Akebia, and nonfinancial support from Roche Diagnostics outside of the work. Dr Grams received travel support from DCI. The authors thank the staff and participants of the ARIC Study for important contributions. Some of the data reported here have been supplied by the US Renal Data System. The interpretation and reporting of these data are the responsibility of the authors and in no way should be seen as an official policy or interpretation of the US government. Received November 25, 2019. Evaluated by 2 external peer reviewers, with direct editorial input from the Editor-in-Chief. Accepted in revised form February 11, 2020.

PY - 2020/7/1

Y1 - 2020/7/1

UR - http://www.scopus.com/inward/record.url?scp=85087111584&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85087111584&partnerID=8YFLogxK

U2 - 10.1016/j.xkme.2020.02.007

DO - 10.1016/j.xkme.2020.02.007

M3 - Article

C2 - 32775995

AN - SCOPUS:85087111584

SN - 2590-0595

VL - 2

SP - 502

EP - 504

JO - Kidney Medicine

JF - Kidney Medicine

IS - 4

ER -