Apo-E genotype was not significantly related to cognitive performance in 157 Alzheimer's disease patients. However, patients homozygous for the ε4 allele appeared most impaired on global cognition but least impaired on language measures. Further study with larger samples may reveal that Apo-E genotype accounts for some of the variability in cognitive deficits observed in Alzheimer's disease.
|Original language||English (US)|
|Number of pages||3|
|Journal||Journal of Neuropsychiatry and Clinical Neurosciences|
|State||Published - Jan 1 1996|
ASJC Scopus subject areas
- Clinical Neurology
- Psychiatry and Mental health