Apicomplexan gliding motility and host cell invasion: Overhauling the motor model

Stefan H.I. Kappe, Carlos A. Buscaglia, Lawrence W. Bergman, Isabelle Coppens, Victor Nussenzweig

Research output: Contribution to journalArticle

Abstract

A unique actomyosin motor powers both host cell invasion and locomotion of apicomplexan invasive stages. This article integrates a revised model of some of the recent advances in our understanding of the components and the overall molecular architecture of this intriguing motion system. Many questions remain, however, regarding the dynamics and regulation of the motor complex.

Original languageEnglish (US)
Pages (from-to)13-16
Number of pages4
JournalTrends in parasitology
Volume20
Issue number1
DOIs
StatePublished - Jan 2004
Externally publishedYes

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

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