TY - JOUR
T1 - Apicomplexan gliding motility and host cell invasion
T2 - Overhauling the motor model
AU - Kappe, Stefan H.I.
AU - Buscaglia, Carlos A.
AU - Bergman, Lawrence W.
AU - Coppens, Isabelle
AU - Nussenzweig, Victor
N1 - Funding Information:
We apologize to people whose work was not referenced due to limited space. Our work was supported by grants from the National Institutes of Health to S.H.I.K., V.N. and L.W.B. We thank Con J. Beckers and Louis D. Sibley for sharing with us their unpublished data. C.A.B. is a recipient of a Bernard Levine fellowship.
PY - 2004/1
Y1 - 2004/1
N2 - A unique actomyosin motor powers both host cell invasion and locomotion of apicomplexan invasive stages. This article integrates a revised model of some of the recent advances in our understanding of the components and the overall molecular architecture of this intriguing motion system. Many questions remain, however, regarding the dynamics and regulation of the motor complex.
AB - A unique actomyosin motor powers both host cell invasion and locomotion of apicomplexan invasive stages. This article integrates a revised model of some of the recent advances in our understanding of the components and the overall molecular architecture of this intriguing motion system. Many questions remain, however, regarding the dynamics and regulation of the motor complex.
UR - http://www.scopus.com/inward/record.url?scp=0347990475&partnerID=8YFLogxK
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U2 - 10.1016/j.pt.2003.10.011
DO - 10.1016/j.pt.2003.10.011
M3 - Article
C2 - 14700584
AN - SCOPUS:0347990475
SN - 1471-4922
VL - 20
SP - 13
EP - 16
JO - Trends in parasitology
JF - Trends in parasitology
IS - 1
ER -