Antiretroviral use among active injection-drug users: The role of patient-provider engagement and structural factors

Amy Ruth Knowlton, Julia H. Arnsten, Lois Eldred, James D. Wilkinson, Starley B. Shade, Amy S. Bohnert, Cui Yang, Lawrence S Wissow, David W. Purcell

Research output: Contribution to journalArticle

Abstract

HIV-seropositive, active injection-drug users (IDUs), compared with other HIV populations, continue to have low rates of highly active antiretroviral therapy (HAART) use, contributing to disparities in their HIV health outcomes. We sought to identify individual-level, interpersonal, and structural factors associated with HAART use among active IDUs to inform comprehensive, contextually tailored intervention to improve the HAART use of IDUs. Prospective data from three semiannual assessments were combined, and logistic general estimating equations were used to identify variables associated with taking HAART 6 months later. Participants were a community sample of HIV-seropositive, active IDUs enrolled in the INSPIRE study, a U.S. multisite (Baltimore, Miami, New York, San Francisco) prevention intervention. The analytic sample included 1,225 observations, and comprised 62% males, 75% active drug users, 75% non-Hispanic blacks, and 55% with a CD4 count

Original languageEnglish (US)
Pages (from-to)421-428
Number of pages8
JournalAIDS Patient Care and STDs
Volume24
Issue number7
DOIs
StatePublished - Jul 1 2010

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Patient Participation
Drug Users
Highly Active Antiretroviral Therapy
Injections
HIV
Baltimore
San Francisco
CD4 Lymphocyte Count
Health
Population

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Infectious Diseases
  • Medicine(all)

Cite this

Antiretroviral use among active injection-drug users : The role of patient-provider engagement and structural factors. / Knowlton, Amy Ruth; Arnsten, Julia H.; Eldred, Lois; Wilkinson, James D.; Shade, Starley B.; Bohnert, Amy S.; Yang, Cui; Wissow, Lawrence S; Purcell, David W.

In: AIDS Patient Care and STDs, Vol. 24, No. 7, 01.07.2010, p. 421-428.

Research output: Contribution to journalArticle

Knowlton, Amy Ruth ; Arnsten, Julia H. ; Eldred, Lois ; Wilkinson, James D. ; Shade, Starley B. ; Bohnert, Amy S. ; Yang, Cui ; Wissow, Lawrence S ; Purcell, David W. / Antiretroviral use among active injection-drug users : The role of patient-provider engagement and structural factors. In: AIDS Patient Care and STDs. 2010 ; Vol. 24, No. 7. pp. 421-428.
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