Abstract
Four groups of women were studied to determine whether low-level antinuclear antibody titers are associated with a higher risk for pregnancy loss. Group A consisted of 30 patients with a history of unexplained fetal losses. Group B consisted of 30 women with "explained" fetal losses (e.g., uterine septum or luteal phase defect). Ages and number of losses were comparable between the women in groups A and B. Group C consisted of 61 healthy pregnant women. Group D involved 61 healthy nonpregnant women of reproductive age. In groups A and B, 40% and 53.3% of the respective patients had antinuclear antibody titers ≥1 : 40. In groups C and D the frequencies of positive antinuclear antibody titers were 8.2% and 5.6%, respectively. This study demonstrates a high prevalence of low-titer antinuclear antibody-positive serum in patients with explained and unexplained pregnancy losses.
Original language | English (US) |
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Pages (from-to) | 1493-1497 |
Number of pages | 5 |
Journal | American journal of obstetrics and gynecology |
Volume | 163 |
Issue number | 5 PART 1 |
DOIs | |
State | Published - Nov 1990 |
Keywords
- Repeated pregnancy wastage or losses
- antinuclear antibody
- habitual abortion
ASJC Scopus subject areas
- Obstetrics and Gynecology