Antimicrobial resistance and urinary tract infection recurrence

Caleb P. Nelson; Alejandro Hoberman; Nader Shaikh; Ron Keren; Ranjiv Mathews; Saul P. Greenfield; Tej K. Mattoo; Nathan Gotman; Anastasia Ivanova; Marva Moxey-Mims; Myra A. Carpenter; Russell W. Chesney

doi:10.1542/peds.2015-2490

Antimicrobial resistance and urinary tract infection recurrence

Caleb P. Nelson, Alejandro Hoberman, Nader Shaikh, Ron Keren, Ranjiv Mathews, Saul P. Greenfield, Tej K. Mattoo, Nathan Gotman, Anastasia Ivanova, Marva Moxey-Mims, Myra A. Carpenter, Russell W. Chesney

School of Medicine

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

Background: The Randomized Intervention for Children with Vesicoureteral Reflux (RIVUR) trial found that recurrent urinary tract infections (rUTI) with resistant organisms were more common in the trimethoprim-sulfamethoxazole prophylaxis (TSP) arm. We describe factors associated with trimethoprim-sulfamethoxazole (TMP-SMX) resistance of rUTIs in RIVUR. Methods: Children aged 2 to 71 months with first or second UTI (index UTI) and grade I to IV vesicoureteral reflux (VUR) were randomized to TSP or placebo and followed for 2 years. Factors associated with TMP-SMX-resistant rUTI were evaluated. Results: Among 571 included children, 48% were

Original language	English (US)
Journal	Pediatrics
Volume	137
Issue number	4
DOIs	https://doi.org/10.1542/peds.2015-2490
State	Published - Apr 1 2016

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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10.1542/peds.2015-2490

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title = "Antimicrobial resistance and urinary tract infection recurrence",

abstract = "Background: The Randomized Intervention for Children with Vesicoureteral Reflux (RIVUR) trial found that recurrent urinary tract infections (rUTI) with resistant organisms were more common in the trimethoprim-sulfamethoxazole prophylaxis (TSP) arm. We describe factors associated with trimethoprim-sulfamethoxazole (TMP-SMX) resistance of rUTIs in RIVUR. Methods: Children aged 2 to 71 months with first or second UTI (index UTI) and grade I to IV vesicoureteral reflux (VUR) were randomized to TSP or placebo and followed for 2 years. Factors associated with TMP-SMX-resistant rUTI were evaluated. Results: Among 571 included children, 48% were ",

author = "Nelson, {Caleb P.} and Alejandro Hoberman and Nader Shaikh and Ron Keren and Ranjiv Mathews and Greenfield, {Saul P.} and Mattoo, {Tej K.} and Nathan Gotman and Anastasia Ivanova and Marva Moxey-Mims and Carpenter, {Myra A.} and Chesney, {Russell W.}",

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TY - JOUR

T1 - Antimicrobial resistance and urinary tract infection recurrence

AU - Nelson, Caleb P.

AU - Hoberman, Alejandro

AU - Shaikh, Nader

AU - Keren, Ron

AU - Mathews, Ranjiv

AU - Greenfield, Saul P.

AU - Mattoo, Tej K.

AU - Gotman, Nathan

AU - Ivanova, Anastasia

AU - Moxey-Mims, Marva

AU - Carpenter, Myra A.

AU - Chesney, Russell W.

PY - 2016/4/1

Y1 - 2016/4/1

N2 - Background: The Randomized Intervention for Children with Vesicoureteral Reflux (RIVUR) trial found that recurrent urinary tract infections (rUTI) with resistant organisms were more common in the trimethoprim-sulfamethoxazole prophylaxis (TSP) arm. We describe factors associated with trimethoprim-sulfamethoxazole (TMP-SMX) resistance of rUTIs in RIVUR. Methods: Children aged 2 to 71 months with first or second UTI (index UTI) and grade I to IV vesicoureteral reflux (VUR) were randomized to TSP or placebo and followed for 2 years. Factors associated with TMP-SMX-resistant rUTI were evaluated. Results: Among 571 included children, 48% were

AB - Background: The Randomized Intervention for Children with Vesicoureteral Reflux (RIVUR) trial found that recurrent urinary tract infections (rUTI) with resistant organisms were more common in the trimethoprim-sulfamethoxazole prophylaxis (TSP) arm. We describe factors associated with trimethoprim-sulfamethoxazole (TMP-SMX) resistance of rUTIs in RIVUR. Methods: Children aged 2 to 71 months with first or second UTI (index UTI) and grade I to IV vesicoureteral reflux (VUR) were randomized to TSP or placebo and followed for 2 years. Factors associated with TMP-SMX-resistant rUTI were evaluated. Results: Among 571 included children, 48% were

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JO - Pediatrics

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Antimicrobial resistance and urinary tract infection recurrence

Abstract

ASJC Scopus subject areas

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